Geoffrey Petit1, Vladimir Grosbois2, Karine Chalvet-Monfray3, Alain Ducos4, Daniel Desmecht5, Guy-Pierre Martineau6, Anouk Decors7. 1. Université Clermont Auvergne, INRAE, VetAgro Sup, UMR EPIA, F-63122 Saint-Genès-Champanelle, France; Université de Lyon, INRAE, VetAgro Sup, UMR EPIA, F-69280 Marcy l'Etoile, France; CIRAD, UMR ASTRE, F-34398 Montpellier, France. Electronic address: geoffrey.petit@outlook.fr. 2. CIRAD, UMR ASTRE, F-34398 Montpellier, France; INRA, UMR1309 ASTRE, F-34398 Montpellier, France. Electronic address: vladimir.grosbois@cirad.fr. 3. Université Clermont Auvergne, INRAE, VetAgro Sup, UMR EPIA, F-63122 Saint-Genès-Champanelle, France; Université de Lyon, INRAE, VetAgro Sup, UMR EPIA, F-69280 Marcy l'Etoile, France. Electronic address: karine.chalvet-monfray@vetagro-sup.fr. 4. GenPhySE, Université de Toulouse, INRA, ENVT, Castanet Tolosan, France. Electronic address: a.ducos@envt.fr. 5. FARAH Research Center, Faculty of Veterinary Medicine, Université de Liège, Sart Tilman B43, B-4000 Liège, Belgium. Electronic address: daniel.desmecht@ulg.ac.be. 6. Université de Toulouse, ENVT, Toulouse, France. Electronic address: g.martineau@envt.fr. 7. Office national de la chasse et de la faune sauvage, Auffargis, France. Electronic address: anouk.decors@oncfs.gouv.fr.
Abstract
BACKGROUND: In 2013, an outbreak of edema disease in a population of wild boars (Sus scrofa) took place. This was the first described case as reported worldwide. An enterotoxigenic Escherichia coli (presenting the Stx2e and F18 virulence factors) is the main pathogen for this disease in wild boar. The alpha-1-fucosyltransferase gene (FUT1) has been identified as the gene regulating the expression of the receptor for E. coli stx2e F18 bacteria in domestic pigs affected by the disease. The genotypic frequencies of the FUT1 gene in European wild boars have not yet been investigated. The genotypes of wild boars for this gene were determined in four French departments with or without edema diseases cases. RESULTS: All of the wild boars analyzed had a genotype susceptible to the disease (GG or AG). The recessive, resistant A allele was found for the first time in wild boars, but in a very small proportion of individuals (7/222). No statistical differences were found between healthy hunted wild boars versus wild boars found dead by edema disease or among the four French departments. CONCLUSIONS: These results suggest that further mortality due to edema disease remains possible in wild boars in France.
BACKGROUND: In 2013, an outbreak of edema disease in a population of wild boars (Sus scrofa) took place. This was the first described case as reported worldwide. An enterotoxigenic Escherichia coli (presenting the Stx2e and F18 virulence factors) is the main pathogen for this disease in wild boar. The alpha-1-fucosyltransferase gene (FUT1) has been identified as the gene regulating the expression of the receptor for E. coli stx2e F18 bacteria in domestic pigs affected by the disease. The genotypic frequencies of the FUT1 gene in European wild boars have not yet been investigated. The genotypes of wild boars for this gene were determined in four French departments with or without edema diseases cases. RESULTS: All of the wild boars analyzed had a genotype susceptible to the disease (GG or AG). The recessive, resistant A allele was found for the first time in wild boars, but in a very small proportion of individuals (7/222). No statistical differences were found between healthy hunted wild boars versus wild boars found dead by edema disease or among the four French departments. CONCLUSIONS: These results suggest that further mortality due to edema disease remains possible in wild boars in France.