Literature DB >> 32311331

Unfolded Protein Response (UPR) Controls Major Senescence Hallmarks.

Corinne Abbadie1, Olivier Pluquet2.   

Abstract

Senescence is a complex cellular state, which can be considered as a stress response phenotype. However, the mechanisms through which cells acquire and maintain this phenotype are not fully understood. In this paper, it is argued that the unfolded protein response (UPR) may represent a signalling platform that is associated with the major senescence hallmarks.
Copyright © 2020 Elsevier Ltd. All rights reserved.

Keywords:  endoplasmic reticulum; proteostasis; secretome, metabolism; senescence; unfolded protein response

Mesh：

Year:  2020        PMID： 32311331     DOI： 10.1016/j.tibs.2020.02.005

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  10 in total

1.  New Evidence of Renal and Cardiovascular Alterations Promoted by Bisphenol A.

Authors:  Rafael Moreno-Gómez-Toledano; María I Arenas; Esperanza Vélez-Vélez; Marta Saura; Ricardo J Bosch
Journal:  Biomolecules       Date:  2021-11-08

2.  Bisphenol A Induces Accelerated Cell Aging in Murine Endothelium.

Authors:  Rafael Moreno-Gómez-Toledano; Sandra Sánchez-Esteban; Alberto Cook; Marta Mínguez-Moratinos; Rafael Ramírez-Carracedo; Paula Reventún; María Delgado-Marín; Ricardo J Bosch; Marta Saura
Journal:  Biomolecules       Date:  2021-09-29

Review 3.  Cellular senescence links mitochondria-ER contacts and aging.

Authors:  Dorian V Ziegler; Nadine Martin; David Bernard
Journal:  Commun Biol       Date:  2021-11-24

4.  The mTOR inhibitor Rapamycin protects from premature cellular senescence early after experimental kidney transplantation.

Authors:  Uwe Hoff; Denise Markmann; Daniela Thurn-Valassina; Melina Nieminen-Kelhä; Zulrahman Erlangga; Jessica Schmitz; Jan Hinrich Bräsen; Klemens Budde; Anette Melk; Björn Hegner
Journal:  PLoS One       Date:  2022-04-21       Impact factor: 3.752

5.  ER-Stress and Senescence Coordinately Promote Endothelial Barrier Dysfunction in Diabetes-Induced Atherosclerosis.

Authors:  Sameen Fatima; Saira Ambreen; Akash Mathew; Ahmed Elwakiel; Anubhuti Gupta; Kunal Singh; Shruthi Krishnan; Rajiv Rana; Hamzah Khawaja; Dheerendra Gupta; Jayakumar Manoharan; Christian Besler; Ulrich Laufs; Shrey Kohli; Berend Isermann; Khurrum Shahzad
Journal:  Nutrients       Date:  2022-07-06       Impact factor: 6.706

Review 6.  From the divergence of senescent cell fates to mechanisms and selectivity of senolytic drugs.

Authors:  Valentin L'Hôte; Carl Mann; Jean-Yves Thuret
Journal:  Open Biol       Date:  2022-09-21       Impact factor: 7.124

Review 7.  Vascular Stress Signaling in Hypertension.

Authors:  Stephanie M Cicalese; Josiane Fernandes da Silva; Fernanda Priviero; R Clinton Webb; Satoru Eguchi; Rita C Tostes
Journal:  Circ Res       Date:  2021-04-01       Impact factor: 17.367

Review 8.  Targeting Molecular Mechanism of Vascular Smooth Muscle Senescence Induced by Angiotensin II, A Potential Therapy via Senolytics and Senomorphics.

Authors:  Keisuke Okuno; Stephanie Cicalese; Katherine J Elliott; Tatsuo Kawai; Tomoki Hashimoto; Satoru Eguchi
Journal:  Int J Mol Sci       Date:  2020-09-09       Impact factor: 5.923

Review 9.  Senescence-Induced Chemoresistance in Triple Negative Breast Cancer and Evolution-Based Treatment Strategies.

Authors:  Anindita Chakrabarty; Shayantani Chakraborty; Ranjini Bhattacharya; Goutam Chowdhury
Journal:  Front Oncol       Date:  2021-06-24       Impact factor: 6.244

10.  MHY1485 enhances X-irradiation-induced apoptosis and senescence in tumor cells.

Authors:  Lue Sun; Kumi Morikawa; Yu Sogo; Yuki Sugiura
Journal:  J Radiat Res       Date:  2021-09-13       Impact factor: 2.724
  10 in total

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