Literature DB >> 3231072

Comparison of regeneration across a vascularized versus conventional nerve graft: case report.

S E Mackinnon1, L Kelly, D A Hunter.   

Abstract

A histological and functional comparison of regeneration across a vascularized and conventional nerve graft was carried out in a clinical case. The two branches of the medial antebrachial cutaneous nerve were used to neurotize the median nerve at the wrist. The superficial branch of the radial nerve (vascularized nerve graft) and a conventional sural nerve graft were used as the interposition grafts between the two branches of the medial antebrachial cutaneous nerve and the median nerve. This nerve grafting procedure was carried out in two stages. The proximal neurorrhaphy was carried out 7 months prior to the distal nerve repair. Biopsies were taken from the distal portions of the vascularized radial sensory nerve and the conventional sural nerve at the time of the second procedure. Histological evaluation demonstrated superior regeneration across the vascularized nerve graft. Subjectively, the patient described better sensory recovery in the territory innervated by the vascularized nerve graft. Sensory testing in the two territories demonstrated better sensibility in the territory innervated by the vascularized nerve graft.

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Mesh:

Year:  1988        PMID: 3231072     DOI: 10.1002/micr.1920090403

Source DB:  PubMed          Journal:  Microsurgery        ISSN: 0738-1085            Impact factor:   2.425


  4 in total

1.  Vascularized nerve grafts and vascularized fascia for upper extremity nerve reconstruction.

Authors:  Julia K Terzis; Vasileios K Kostopoulos
Journal:  Hand (N Y)       Date:  2009-04-18

2.  Increasing Nerve Autograft Length Increases Senescence and Reduces Regeneration.

Authors:  Gwendolyn M Hoben; Xueping Ee; Lauren Schellhardt; Ying Yan; Daniel A Hunter; Amy M Moore; Alison K Snyder-Warwick; Sheila Stewart; Susan E Mackinnon; Matthew D Wood
Journal:  Plast Reconstr Surg       Date:  2018-10       Impact factor: 4.730

3.  Nerve recovery from treatment with a vascularized nerve graft compared to an autologous non-vascularized nerve graft in animal models: A systematic review and meta-analysis.

Authors:  Berend O Broeren; Liron S Duraku; Caroline A Hundepool; Erik T Walbeehm; J Michiel Zuidam; Carlijn R Hooijmans; Tim De Jong
Journal:  PLoS One       Date:  2021-12-02       Impact factor: 3.240

4.  Facial Nerve Reconstruction with Free Vascularized Composite Nerve Flap from Intrapetrous Portion to Terminal Branches-Case Report.

Authors:  Pedro C Cavadas; Magdalena Baklinska
Journal:  Indian J Plast Surg       Date:  2021-06-30
  4 in total

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