Literature DB >> 323093

The value of calcium dobesilate in the treatment of diabetic retinopathy. A controlled clinical trial.

H W Larsen, E Sander, R Hoppe.   

Abstract

The effect of calcium dobesilate on capillary resistance and background retinopathy was compared with placebo in a double-blind cross-over trial on 18 diabetics. Each treatment lasted 8 months. The trial produced no evidence in favour of a significant beneficial effect of calcium dobesilate on the capillary resistance in diabetics or on the course of the diabetic retinopathy.

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Year:  1977        PMID： 323093     DOI： 10.1007/bf00745136

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


  8 in total

1.  [Exudative diabetic retinopathy. A fluorescence angiography study].

Authors:  H Freyler
Journal:  Ophthalmologica       Date:  1975       Impact factor: 3.250

2.  [Decrease of vascular fragility in diabetic retinopathy through calciumdobesilate (author's transl)].

Authors:  H Freyler; W Sehorst
Journal:  Klin Monbl Augenheilkd       Date:  1974-02       Impact factor: 0.700

3.  Capillary fragility and doxium. A controlled clinical trial.

Authors:  R Rasch
Journal:  Diabetologia       Date:  1973-12       Impact factor: 10.122

4.  Caclium dobesilate in diabetic retinopathy.

Authors:  R Sévin; J F Cuendet
Journal:  Ophthalmologica       Date:  1969       Impact factor: 3.250

5.  [Treatment of diabetic retinopathy and recurrent hemorrhages into the vitreous with calcium dobesilate].

Authors:  M Favre
Journal:  Ophthalmologica       Date:  1970       Impact factor: 3.250

6.  The action of calcium dobesilate on capillary permeability in diabetics.

Authors:  R Sévin; J F Cuendet
Journal:  Ophthalmologica       Date:  1971       Impact factor: 3.250

7.  Quantitative measurements of skin capillary resistance in hypophysectomized long-term diabetics.

Authors:  N J Christensen; A B Terkildsen
Journal:  Diabetes       Date:  1971-05       Impact factor: 9.461

8.  Microvascular protection with calcium dobesilate (Doxium) in diabetic retinopathy.

Authors:  H Freyler
Journal:  Ophthalmologica       Date:  1974       Impact factor: 3.250
  8 in total
  4 in total

1.  Effectiveness and cost-benefit analysis of intensive treatment and teaching programmes for type 1 (insulin-dependent) diabetes mellitus in Moscow--blood glucose versus urine glucose self-monitoring.

Authors:  E G Starostina; M Antsiferov; G R Galstyan; C Trautner; V Jörgens; U Bott; I Mühlhauser; M Berger; I I Dedov
Journal:  Diabetologia       Date:  1994-02       Impact factor: 10.122

2.  Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes.

Authors:  Ermelindo C Leal; João Martins; Paula Voabil; Joana Liberal; Carlo Chiavaroli; Jacques Bauer; José Cunha-Vaz; António F Ambrósio
Journal:  Diabetes       Date:  2010-07-13       Impact factor: 9.461

Review 3.  Update on the Effects of Antioxidants on Diabetic Retinopathy: In Vitro Experiments, Animal Studies and Clinical Trials.

Authors:  Jose Javier Garcia-Medina; Elena Rubio-Velazquez; Elisa Foulquie-Moreno; Ricardo P Casaroli-Marano; Maria Dolores Pinazo-Duran; Vicente Zanon-Moreno; Monica Del-Rio-Vellosillo
Journal:  Antioxidants (Basel)       Date:  2020-06-26

4.  Calcium dobesilate reduces endothelin-1 and high-sensitivity C-reactive protein serum levels in patients with diabetic retinopathy.

Authors:  Alireza Javadzadeh; Amir Ghorbanihaghjo; Farzad Hami Adl; Dima Andalib; Hassan Khojasteh-Jafari; Kamyar Ghabili
Journal:  Mol Vis       Date:  2013-01-10       Impact factor: 2.367
  4 in total

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