Literature DB >> 32308921

Relation Extraction from Clinical Narratives Using Pre-trained Language Models.

Qiang Wei1, Zongcheng Ji1, Yuqi Si1, Jingcheng Du1, Jingqi Wang1, Firat Tiryaki1, Stephen Wu1, Cui Tao1, Kirk Roberts1, Hua Xu1.   

Abstract

Natural language processing (NLP) is useful for extracting information from clinical narratives, and both traditional machine learning methods and more-recent deep learning methods have been successful in various clinical NLP tasks. These methods often depend on traditional word embeddings that are outputs of language models (LMs). Recently, methods that are directly based on pre-trained language models themselves, followed by fine-tuning on the LMs (e.g. the Bidirectional Encoder Representations from Transformers (BERT)), have achieved state-of-the-art performance on many NLP tasks. Despite their success in the open domain and biomedical literature, these pre-trained LMs have not yet been applied to the clinical relation extraction (RE) task. In this study, we developed two different implementations of the BERT model for clinical RE tasks. Our results show that our tuned LMs outperformed previous state-of-the-art RE systems in two shared tasks, which demonstrates the potential of LM-based methods on the RE task. ©2019 AMIA - All rights reserved.

Year:  2020        PMID: 32308921      PMCID: PMC7153059     

Source DB:  PubMed          Journal:  AMIA Annu Symp Proc        ISSN: 1559-4076


  19 in total

1.  RelEx--relation extraction using dependency parse trees.

Authors:  Katrin Fundel; Robert Küffner; Ralf Zimmer
Journal:  Bioinformatics       Date:  2006-12-01       Impact factor: 6.937

2.  2010 i2b2/VA challenge on concepts, assertions, and relations in clinical text.

Authors:  Özlem Uzuner; Brett R South; Shuying Shen; Scott L DuVall
Journal:  J Am Med Inform Assoc       Date:  2011-06-16       Impact factor: 4.497

3.  Automatic extraction of relations between medical concepts in clinical texts.

Authors:  Bryan Rink; Sanda Harabagiu; Kirk Roberts
Journal:  J Am Med Inform Assoc       Date:  2011 Sep-Oct       Impact factor: 4.497

4.  A study of deep learning approaches for medication and adverse drug event extraction from clinical text.

Authors:  Qiang Wei; Zongcheng Ji; Zhiheng Li; Jingcheng Du; Jingqi Wang; Jun Xu; Yang Xiang; Firat Tiryaki; Stephen Wu; Yaoyun Zhang; Cui Tao; Hua Xu
Journal:  J Am Med Inform Assoc       Date:  2020-01-01       Impact factor: 4.497

5.  Recurrent neural networks for classifying relations in clinical notes.

Authors:  Yuan Luo
Journal:  J Biomed Inform       Date:  2017-07-08       Impact factor: 6.317

6.  A Frame-Based NLP System for Cancer-Related Information Extraction.

Authors:  Yuqi Si; Kirk Roberts
Journal:  AMIA Annu Symp Proc       Date:  2018-12-05

Review 7.  Mining electronic health records: towards better research applications and clinical care.

Authors:  Peter B Jensen; Lars J Jensen; Søren Brunak
Journal:  Nat Rev Genet       Date:  2012-05-02       Impact factor: 53.242

8.  The contribution of co-reference resolution to supervised relation detection between bacteria and biotopes entities.

Authors:  Thomas Lavergne; Cyril Grouin; Pierre Zweigenbaum
Journal:  BMC Bioinformatics       Date:  2015-07-13       Impact factor: 3.169

Review 9.  Evaluating temporal relations in clinical text: 2012 i2b2 Challenge.

Authors:  Weiyi Sun; Anna Rumshisky; Ozlem Uzuner
Journal:  J Am Med Inform Assoc       Date:  2013-04-05       Impact factor: 4.497

10.  CLAMP - a toolkit for efficiently building customized clinical natural language processing pipelines.

Authors:  Ergin Soysal; Jingqi Wang; Min Jiang; Yonghui Wu; Serguei Pakhomov; Hongfang Liu; Hua Xu
Journal:  J Am Med Inform Assoc       Date:  2018-03-01       Impact factor: 4.497

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  4 in total

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2.  Extracting postmarketing adverse events from safety reports in the vaccine adverse event reporting system (VAERS) using deep learning.

Authors:  Jingcheng Du; Yang Xiang; Madhuri Sankaranarayanapillai; Meng Zhang; Jingqi Wang; Yuqi Si; Huy Anh Pham; Hua Xu; Yong Chen; Cui Tao
Journal:  J Am Med Inform Assoc       Date:  2021-07-14       Impact factor: 4.497

3.  Clinical concept extraction using transformers.

Authors:  Xi Yang; Jiang Bian; William R Hogan; Yonghui Wu
Journal:  J Am Med Inform Assoc       Date:  2020-12-09       Impact factor: 4.497

4.  Unified Medical Language System resources improve sieve-based generation and Bidirectional Encoder Representations from Transformers (BERT)-based ranking for concept normalization.

Authors:  Dongfang Xu; Manoj Gopale; Jiacheng Zhang; Kris Brown; Edmon Begoli; Steven Bethard
Journal:  J Am Med Inform Assoc       Date:  2020-10-01       Impact factor: 4.497

  4 in total

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