| Literature DB >> 32306801 |
Takahiro Kamiya1,2, Chisako Ito1, Yuriko Fujita1, Shinji Ogura1, Kota Mizuno1,2, Aki Sakurai1, Yoshinobu Aisa1, Tomonori Nakazato1.
Abstract
The Controlling Nutritional Status (CONUT) score predicts the prognosis in several tumors. However, its prognostic significance in multiple myeloma (MM) remains unclear. The present study investigated the correlation between the CONUT score and the survival outcomes of MM patients. A total of 178 patients newly diagnosed with MM were retrospectively enrolled. Patients with a high CONUT score (≥5) had a significantly shorter median overall survival (OS) than those with a low CONUT score (≤4) (33 vs. 57 months, p < .001). In a multivariate analysis among patients with International Staging System (ISS) score of ≤2, a high CONUT score was an independent prognostic covariate for the OS after adjusting for other significant factors (hazard ratio 2.364; 95% confidence interval 1.324-4.220, p = .004). Our results suggest that the CONUT score is a predictor of a poor outcome in patients with MM, particularly in low-ISS-score cases.Entities:
Keywords: CONUT score; Multiple myeloma; prognosis
Mesh：
Year: 2020 PMID： 32306801 DOI： 10.1080/10428194.2020.1749608
Source DB: PubMed Journal: Leuk Lymphoma ISSN： 1026-8022