Literature DB >> 3230569

The role of metabolic factors and blood pressure in the association of obesity with osteoarthritis of the knee.

M A Davis1, W H Ettinger, J M Neuhaus.   

Abstract

The role of systemic/metabolic factors in the association of obesity with knee osteoarthritis (OA) was analyzed using radiographic data, metabolic measures, and blood pressure for 3885 American adults aged 45-74 from the U.S. National Health and Nutrition Examination Survey, 1971-1975 (NHANES I). Obesity was associated with both bilateral and unilateral OA, but more strongly with bilateral OA. Controlling for age, sex, serum cholesterol, serum uric acid, diabetes, body fat distribution, and blood pressure did not significantly reduce the association between obesity and knee OA. Findings from these data are not supportive of a metabolic link between obesity and knee OA.

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Year:  1988        PMID: 3230569

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  16 in total

1.  Overweight: advancing our understanding of its impact on the knee and the hip.

Authors:  Leena Sharma; Alison Chang
Journal:  Ann Rheum Dis       Date:  2007-02       Impact factor: 19.103

Review 2.  Obesity: a preventable risk factor for large joint osteoarthritis which may act through biomechanical factors.

Authors:  A Powell; A J Teichtahl; A E Wluka; F M Cicuttini
Journal:  Br J Sports Med       Date:  2005-01       Impact factor: 13.800

Review 3.  Does excess weight cause osteoarthritis and, if so, why?

Authors:  D T Felson
Journal:  Ann Rheum Dis       Date:  1996-09       Impact factor: 19.103

4.  Osteoarthrosis of the knee in men and women in association with overweight, smoking, and hormone therapy.

Authors:  H Sandmark; C Hogstedt; S Lewold; E Vingård
Journal:  Ann Rheum Dis       Date:  1999-03       Impact factor: 19.103

5.  Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice.

Authors:  Timothy M Griffin; Beverley Fermor; Janet L Huebner; Virginia B Kraus; Ramona M Rodriguiz; William C Wetsel; Li Cao; Lori A Setton; Farshid Guilak
Journal:  Arthritis Res Ther       Date:  2010-07-06       Impact factor: 5.156

6.  Weight changes and the risk of knee osteoarthritis requiring arthroplasty.

Authors:  P Manninen; H Riihimaki; M Heliövaara; O Suomalainen
Journal:  Ann Rheum Dis       Date:  2004-11       Impact factor: 19.103

7.  Risk factors for knee osteoarthritis in Morocco. A case control study.

Authors:  Aziza Mounach; Abderrazak Nouijai; Imad Ghozlani; Mirieme Ghazi; Lahsen Achemlal; Ahmed Bezza; Abdellah El Maghraoui
Journal:  Clin Rheumatol       Date:  2007-08-16       Impact factor: 2.980

8.  Association of metabolic risk factors with cartilage degradation assessed by T2 relaxation time at the knee: data from the osteoarthritis initiative.

Authors:  P M Jungmann; M S Kraus; H Alizai; L Nardo; T Baum; M C Nevitt; C E McCulloch; G B Joseph; J A Lynch; T M Link
Journal:  Arthritis Care Res (Hoboken)       Date:  2013-12       Impact factor: 4.794

9.  Why is obesity associated with osteoarthritis? Insights from mouse models of obesity.

Authors:  Timothy M Griffin; Farshid Guilak
Journal:  Biorheology       Date:  2008       Impact factor: 1.875

10.  Knee osteoarthritis in obese women with cardiometabolic clustering.

Authors:  Maryfran Sowers; Carrie A Karvonen-Gutierrez; Riann Palmieri-Smith; Jon A Jacobson; Yebin Jiang; James A Ashton-Miller
Journal:  Arthritis Rheum       Date:  2009-10-15
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