Literature DB >> 32301273

Donor evaluation in the era of HIV-positive organ transplantation: The importance of the infectious diseases specialist.

Marion Hemmersbach-Miller1,2, Robert P Wood3, Cameron R Wolfe1.   

Abstract

A 61-year-old female with well-controlled human immunodeficiency virus (HIV) and end-stage renal disease was on the kidney transplant waitlist awaiting an organ offer, including from HIV-positive donors through the HIV Organ Policy Equity (HOPE) Act. We present three different scenarios where HIV-positive donor offers were evaluated for this one recipient, discuss the donor evaluation process, explain where the infectious diseases provider fits in this scheme, and describe the challenges encountered by organ procurement organizations. This is the first case under the HOPE Act at our center where discovery of an HIV-specific issue led to a turndown of an organ offer.
© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons.

Entities:  

Keywords:  clinical research/practice; donors and donation; infection and infectious agents-viral; infection and infectious agents-viral: human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS); infectious disease; kidney disease: infectious; kidney transplantation/nephrology

Mesh:

Year:  2020        PMID: 32301273      PMCID: PMC7540733          DOI: 10.1111/ajt.15921

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  16 in total

1.  HIV-Positive-to-HIV-Positive Liver Transplantation.

Authors:  A Calmy; C van Delden; E Giostra; C Junet; L Rubbia Brandt; S Yerly; J-P Chave; C Samer; L Elkrief; J Vionnet; T Berney
Journal:  Am J Transplant       Date:  2016-06-07       Impact factor: 8.086

2.  CD4 Count in HIV- Brain-Dead Donors: Insight into Donor Risk Assessment for HIV+ Donors.

Authors:  Oscar Kenneth Serrano; Scott Kerwin; William D Payne; Timothy L Pruett
Journal:  Transplantation       Date:  2017-04       Impact factor: 4.939

3.  National landscape of HIV+ to HIV+ kidney and liver transplantation in the United States.

Authors:  Amber R Wilk; Robert A Hunter; Maureen A McBride; David K Klassen
Journal:  Am J Transplant       Date:  2019-07-10       Impact factor: 8.086

Review 4.  Infection in Organ Transplantation.

Authors:  J A Fishman
Journal:  Am J Transplant       Date:  2017-03-10       Impact factor: 8.086

5.  Integrase strand transferase inhibitors: the preferred antiretroviral regimen in HIV-positive renal transplantation.

Authors:  Marwan M Azar; Maricar F Malinis; J Moss; Richard N Formica; Merceditas S Villanueva
Journal:  Int J STD AIDS       Date:  2016-07-10       Impact factor: 1.359

Review 6.  The future of HIV Organ Policy Equity Act is now: the state of HIV+ to HIV+ kidney transplantation in the United States.

Authors:  Brian J Boyarsky; Mary Grace Bowring; Ashton A Shaffer; Dorry L Segev; Christine M Durand
Journal:  Curr Opin Organ Transplant       Date:  2019-08       Impact factor: 2.640

7.  High prevalence of HIV-1 transmitted drug-resistance mutations from proviral DNA massively parallel sequencing data of therapy-naïve chronically infected Brazilian blood donors.

Authors:  Rodrigo Pessôa; Sabri S Sanabani
Journal:  PLoS One       Date:  2017-09-27       Impact factor: 3.240

8.  Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted Human Immunodeficiency Virus Type 1 Drug Resistance in a Large US Clinic Population.

Authors:  Soo-Yon Rhee; Dana Clutter; W Jeffrey Fessel; Daniel Klein; Sally Slome; Benjamin A Pinsky; Julia L Marcus; Leo Hurley; Michael J Silverberg; Sergei L Kosakovsky Pond; Robert W Shafer
Journal:  Clin Infect Dis       Date:  2019-01-07       Impact factor: 9.079

9.  Integrase inhibitor (INI) genotypic resistance in treatment-naive and raltegravir-experienced patients infected with diverse HIV-1 clades.

Authors:  Tomas Doyle; David T Dunn; Francesca Ceccherini-Silberstein; Carmen De Mendoza; Frederico Garcia; Erasmus Smit; Esther Fearnhill; Anne-Genevieve Marcelin; Javier Martinez-Picado; Rolf Kaiser; Anna Maria Geretti
Journal:  J Antimicrob Chemother       Date:  2015-08-26       Impact factor: 5.790

Review 10.  Contemporary issues and new challenges in chronic kidney disease amongst people living with HIV.

Authors:  Jack Edward Heron; Corinne Isnard Bagnis; David M Gracey
Journal:  AIDS Res Ther       Date:  2020-03-16       Impact factor: 2.250

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  1 in total

1.  National Landscape of Human Immunodeficiency Virus-Positive Deceased Organ Donors in the United States.

Authors:  William A Werbel; Diane M Brown; Oyinkansola T Kusemiju; Brianna L Doby; Shanti M Seaman; Andrew D Redd; Yolanda Eby; Reinaldo E Fernandez; Niraj M Desai; Jernelle Miller; Gilad A Bismut; Charles S Kirby; Haley A Schmidt; William A Clarke; Michael Seisa; Christos J Petropoulos; Thomas C Quinn; Sander S Florman; Shirish Huprikar; Meenakshi M Rana; Rachel J Friedman-Moraco; Aneesh K Mehta; Peter G Stock; Jennifer C Price; Valentina Stosor; Shikha G Mehta; Alexander J Gilbert; Nahel Elias; Michele I Morris; Sapna A Mehta; Catherine B Small; Ghady Haidar; Maricar Malinis; Jennifer S Husson; Marcus R Pereira; Gaurav Gupta; Jonathan Hand; Varvara A Kirchner; Avinash Agarwal; Saima Aslam; Emily A Blumberg; Cameron R Wolfe; Kevin Myer; R Patrick Wood; Nikole Neidlinger; Sara Strell; Marion Shuck; Harry Wilkins; Matthew Wadsworth; Jennifer D Motter; Jonah Odim; Dorry L Segev; Christine M Durand; Aaron A R Tobian
Journal:  Clin Infect Dis       Date:  2022-06-10       Impact factor: 20.999

  1 in total

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