Yasemin Türk1, Willy Theel2, Astrid van Huisstede3,4, Gert-Jan M van de Geijn5,6, Erwin Birnie6,7, Pieter S Hiemstra8, Jacob K Sont9, Christian Taube8,10, Gert-Jan Braunstahl3,11. 1. Dept of Pulmonology Franciscus Gasthuis & Vlietland Rotterdam The Netherlands y.turk@franciscus.nl. 2. Dept of Physiotherapy, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands. 3. Dept of Pulmonology Franciscus Gasthuis & Vlietland Rotterdam The Netherlands. 4. Dept of Pulmonology, Noordwest Ziekenhuisgroep, Alkmaar, The Netherlands. 5. Dept of Clinical Chemistry, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands. 6. Dept of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. 7. Dept of Statistics and Education, Francis Academy, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands. 8. Dept of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands. 9. Dept of Biomedical Data Sciences, Section Medical Decision Making, Leiden University Medical Center, Leiden, The Netherlands. 10. Dept of Pulmonary Medicine, University Hospital Essen - Ruhrlandklinik, Essen, Germany. 11. Dept of Pulmonology, Erasmus Medical Center, Rotterdam, The Netherlands.
Abstract
OBJECTIVE: To determine the short-term and long-term effects of a high intensity pulmonary rehabilitation programme on asthma control, body composition, lung function and exercise capacity in obese asthma patients. METHODS:Patients with obesity (body mass index (BMI)≥30 kg·m-2) and suboptimal controlled asthma (Asthma Control Questionnaire (ACQ)≥0.75) were randomly assigned to a 3-month pulmonary rehabilitation programme (PR only), pulmonary rehabilitation programme with the use of an internet based self-management support programme (PR+SMS) or usual care. The pulmonary rehabilitation programme included high-intensity interval training, nutritional intervention and psychological group sessions. Patients in the usual care group were advised to lose weight and to exercise. The primary outcome was the difference of change of ACQ between PR only and PR+SMS after 3 months. Total follow-up was 12 months. RESULTS:34 patients were included in the study (14 PR only, nine PR+SMS, 11 control). Compared with patients in usual care, patients in the PR only group had a significant reduction in BMI and significant improvements in asthma control, exercise capacity and aerobic capacity after 3 months. These improvements persisted during 12 months of follow-up. No difference in ACQ between PR+SMS and PR only groups was observed. However, users of the SMS programme had a significantly lower BMI after 12 months compared with subjects in the PR only group. CONCLUSION: A high-intensity pulmonary rehabilitation programme provides sustained improvements in asthma control, body composition and exercise capacity in obese asthmatics that are not optimally controlled and, therefore, should be considered in the treatment of these patients.
RCT Entities:
OBJECTIVE: To determine the short-term and long-term effects of a high intensity pulmonary rehabilitation programme on asthma control, body composition, lung function and exercise capacity in obese asthmapatients. METHODS:Patients with obesity (body mass index (BMI)≥30 kg·m-2) and suboptimal controlled asthma (Asthma Control Questionnaire (ACQ)≥0.75) were randomly assigned to a 3-month pulmonary rehabilitation programme (PR only), pulmonary rehabilitation programme with the use of an internet based self-management support programme (PR+SMS) or usual care. The pulmonary rehabilitation programme included high-intensity interval training, nutritional intervention and psychological group sessions. Patients in the usual care group were advised to lose weight and to exercise. The primary outcome was the difference of change of ACQ between PR only and PR+SMS after 3 months. Total follow-up was 12 months. RESULTS: 34 patients were included in the study (14 PR only, nine PR+SMS, 11 control). Compared with patients in usual care, patients in the PR only group had a significant reduction in BMI and significant improvements in asthma control, exercise capacity and aerobic capacity after 3 months. These improvements persisted during 12 months of follow-up. No difference in ACQ between PR+SMS and PR only groups was observed. However, users of the SMS programme had a significantly lower BMI after 12 months compared with subjects in the PR only group. CONCLUSION: A high-intensity pulmonary rehabilitation programme provides sustained improvements in asthma control, body composition and exercise capacity in obese asthmatics that are not optimally controlled and, therefore, should be considered in the treatment of these patients.
Authors: Xiaoyue Song; Cynthia Hallensleben; Weihong Zhang; Zongliang Jiang; Hongxia Shen; Robbert J J Gobbens; Rianne M J J Van Der Kleij; Niels H Chavannes; Anke Versluis Journal: J Med Internet Res Date: 2021-03-31 Impact factor: 5.428
Authors: Helen Clare Ricketts; Varun Sharma; Femke Steffensen; Anna Goodfellow; Elaine Mackay; Gordon MacDonald; Duncan S Buchan; Rekha Chaudhuri; Douglas C Cowan Journal: BMC Pulm Med Date: 2022-09-24 Impact factor: 3.320
Authors: Annabelle Bédard; Zhen Li; Wassila Ait-Hadad; Carlos A Camargo; Bénédicte Leynaert; Christophe Pison; Orianne Dumas; Raphaëlle Varraso Journal: Int J Environ Res Public Health Date: 2021-03-15 Impact factor: 3.390