Literature DB >> 32297005

Fatigue-related modulation of low-frequency common drive to motor units.

Ing-Shiou Hwang1,2, Yen-Ting Lin3, Chien-Chun Huang4, Yi-Ching Chen5,6.   

Abstract

PURPOSE: This study investigated fatigue-related modulation of common neural inputs to motor units (MUs) under 5 Hz, which determines force precision control.
METHODS: Twenty-seven adults performed a sequence of fatiguing contractions. The participants were assessed with a static isometric index abduction at 20% maximal voluntary contraction in the pre-test and post-test. Discharge characteristics of MUs of the first dorsal interosseous muscle were analyzed with decomposed EMG signals.
RESULTS: Along with increases in the mean (58.40 ± 11.76 ms → 62.55 ± 10.83 ms, P = 0.029) and coefficient of variation (0.204 ± .014 → 0.215 ± 0.017, P = 0.002) in inter-spike intervals, the fatiguing contraction caused reductions in the mean frequency (16.84 ± 3.31 Hz → 15.59 ± 3.21 Hz, P = 0.027) and spectral dispersions (67.54 ± 4.49 → 62.64 ± 6.76 Hz, P = 0.007) of common neural drive, as estimated with smoothed cumulative motor unit spike trains (SCMUSTs). Stabilogram diffusion analysis of SCMUSTs revealed significant fatigue-related reductions in the long-term effective diffusion coefficient (1.91 ± 0.77 Hz2/s → 1.61 ± 0.61 Hz2/s, P = 0.020) and long-term scaling exponent (0.480 ± 0.013 Hz2/s → 0.471 ± 0.017 Hz2/s, P = 0.014). After fatiguing contraction, mutual information of force fluctuations and SCMUSTs was augmented roughly by 12.95% (P = 0.041).
CONCLUSIONS: Muscular fatigue could compress and shift the low-frequency common drive to MUs toward lower spectral bands, thereby enhancing transmission of twitch forces through the muscle-tendon complex with a low-pass filter property. The fatigue-induced changes involve increased closed-loop control of the common modulation of MU discharge rates.

Entities:  

Keywords:  Discharge–force relation; EMG; Fatigue; Firing rate; Stabilogram diffusion analysis

Mesh:

Year:  2020        PMID: 32297005     DOI: 10.1007/s00421-020-04363-z

Source DB:  PubMed          Journal:  Eur J Appl Physiol        ISSN: 1439-6319            Impact factor:   3.078


  47 in total

1.  The proportion of common synaptic input to motor neurons increases with an increase in net excitatory input.

Authors:  Anna Margherita Castronovo; Francesco Negro; Silvia Conforto; Dario Farina
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2.  Rate coding is compressed but variability is unaltered for motor units in a hand muscle of old adults.

Authors:  Benjamin K Barry; Michael A Pascoe; Mark Jesunathadas; Roger M Enoka
Journal:  J Neurophysiol       Date:  2007-03-14       Impact factor: 2.714

3.  Effects of fatigue on intermuscular common drive to the quadriceps femoris.

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Journal:  Int J Neurosci       Date:  2012-06-21       Impact factor: 2.292

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Journal:  J Neurophysiol       Date:  1998-09       Impact factor: 2.714

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Authors:  J J Collins; C J De Luca
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Review 7.  Autonomic responses to exercise: group III/IV muscle afferents and fatigue.

Authors:  Markus Amann; Simranjit K Sidhu; Joshua C Weavil; Tyler S Mangum; Massimo Venturelli
Journal:  Auton Neurosci       Date:  2014-10-23       Impact factor: 3.145

8.  Recruitment order of motor units in human vastus lateralis muscle is maintained during fatiguing contractions.

Authors:  Alexander Adam; Carlo J De Luca
Journal:  J Neurophysiol       Date:  2003-11       Impact factor: 2.714

9.  Paradigm Shifts in Voluntary Force Control and Motor Unit Behaviors with the Manipulated Size of Visual Error Perception.

Authors:  Yi-Ching Chen; Yen-Ting Lin; Gwo-Ching Chang; Ing-Shiou Hwang
Journal:  Front Physiol       Date:  2017-03-13       Impact factor: 4.566

10.  Variations in Static Force Control and Motor Unit Behavior with Error Amplification Feedback in the Elderly.

Authors:  Yi-Ching Chen; Linda L Lin; Yen-Ting Lin; Chia-Ling Hu; Ing-Shiou Hwang
Journal:  Front Hum Neurosci       Date:  2017-11-08       Impact factor: 3.169

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