Literature DB >> 32295601

Correlates of uptake of optimal doses of sulfadoxine-pyrimethamine for prevention of malaria during pregnancy in East-Central Uganda.

Mbonye K Martin1, Kirwana B Venantius2, Ndugga Patricia3, Kikaire Bernard4,5, Baleeta Keith6, Kabagenyi Allen3, Asiimwe Godfrey7, Twesigye Rogers6, Kadengye T Damazo8, Byonanebye M Dathan9.   

Abstract

BACKGROUND: In 2012, the World Health Organization recommended that pregnant women in malaria-endemic countries complete at least three (optimal) doses of intermittent preventive treatment (IPTp) using sulfadoxine-pyrimethamine (SP) to prevent malaria and related adverse events during pregnancy. Uganda adopted this recommendation, but uptake remains low in East-Central and information to explain this low uptake remains scanty. This analysis determined correlates of uptake of optimal doses of IPTp-SP in East-Central Uganda.
METHODS: This was a secondary analysis of the 2016 Uganda Demographic Health Survey data on 579 women (15-49 years) who attended at least one antenatal care (ANC) visit and had a live birth within 2 years preceding the survey. Uptake of IPTp-SP was defined as optimal if a woman received at least three doses; partial if they received 1-2 doses or none if they received no dose. Multivariate analysis using multinomial logistic regression was used to determine correlates of IPTp-SP uptake.
RESULTS: Overall, 22.3% of women received optimal doses of IPTp-SP, 48.2% partial and 29.5% none. Attending ANC at a lower-level health centre relative to a hospital was associated with reduced likelihood of receiving optimal doses of IPTp-SP. Belonging to other religious faiths relative to Catholic, belonging to a household in the middle relative to poorest wealth index, and age 30 and above years relative to 25-29 years were associated with higher likelihood of receiving optimal doses of IPTp-SP.
CONCLUSIONS: In East-Central Uganda, uptake of optimal doses of IPTp-SP is very low. Improving institutional delivery and household wealth, involving religious leaders in programmes to improve uptake of IPTp-SP, and strengthening IPTp-SP activities at lower level health centers may improve uptake of IPTp-SP in the East-Central Uganda.

Entities:  

Keywords:  Demographic and health survey; Intermittent preventive treatment during pregnancy; Malaria; Uganda

Year:  2020        PMID: 32295601     DOI: 10.1186/s12936-020-03230-8

Source DB:  PubMed          Journal:  Malar J        ISSN: 1475-2875            Impact factor:   2.979


  3 in total

1.  Risk factors for placental malaria, sulfadoxine-pyrimethamine doses, and birth outcomes in a rural to urban prospective cohort study on the Bandiagara Escarpment and Bamako, Mali.

Authors:  Claudius Vincenz; Zachary Dolo; Serou Saye; Jennie L Lovett; Beverly I Strassmann
Journal:  Malar J       Date:  2022-03-31       Impact factor: 2.979

2.  Factors influencing health workers' compliance with the WHO intermittent preventive treatment for malaria in pregnancy recommendations in the Northern Region, Ghana.

Authors:  Abdul Gafaru Mohammed; Dwomoh Duah; Ernest Kenu; Justice Nonvignon; Alex Manu; Harriet Affran Bonful
Journal:  Malar J       Date:  2022-09-24       Impact factor: 3.469

Review 3.  Chloroquine and Sulfadoxine-Pyrimethamine Resistance in Sub-Saharan Africa-A Review.

Authors:  Alexandra T Roux; Leah Maharaj; Olukunle Oyegoke; Oluwasegun P Akoniyon; Matthew Adekunle Adeleke; Rajendra Maharaj; Moses Okpeku
Journal:  Front Genet       Date:  2021-06-25       Impact factor: 4.599

  3 in total

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