Literature DB >> 32294939

Steering the Clinical Translation of Delivery Systems for Drugs and Health Products.

Rosario Pignatello1, Pietro Matricardi2.   

Abstract

Besides the feasibility for industrial scale-up, accelerating the translation from bench to bedside of new technological strategies for controlled delivery and targeting of drugs and other actives relevant for health management, such as medical devices and nutraceuticals, would benefit from an even earlier evaluation in pre-clinical models and clinical settings. At the same time, translational medicine also performs in the opposite direction, incorporating clinical needs and observations into scientific hypotheses and innovative technological proposals. With these aims, the sessions proposed for the 2019 CRS Italy Chapter Workshop will introduce the experience of Italian and worldwide researchers on how to foster the actual work in controlled release and drug delivery towards a reliable pre-clinical and clinical assessment.

Entities:  

Keywords:  bioinformatics; clinical trials; controlled release; drug delivery; medical devices; nutraceuticals

Year:  2020        PMID: 32294939      PMCID: PMC7238002          DOI: 10.3390/pharmaceutics12040350

Source DB:  PubMed          Journal:  Pharmaceutics        ISSN: 1999-4923            Impact factor:   6.321


  78 in total

1.  Model of chemotherapy-induced myelosuppression with parameter consistency across drugs.

Authors:  Lena E Friberg; Anja Henningsson; Hugo Maas; Laurent Nguyen; Mats O Karlsson
Journal:  J Clin Oncol       Date:  2002-12-15       Impact factor: 44.544

Review 2.  Active methods of drug loading into liposomes: recent strategies for stable drug entrapment and increased in vivo activity.

Authors:  Jerzy Gubernator
Journal:  Expert Opin Drug Deliv       Date:  2011-04-15       Impact factor: 6.648

3.  Stem cell-extracellular vesicles as drug delivery systems: New frontiers for silk/curcumin nanoparticles.

Authors:  Sara Perteghella; Barbara Crivelli; Laura Catenacci; Milena Sorrenti; Giovanna Bruni; Vittorio Necchi; Barbara Vigani; Marzio Sorlini; Maria Luisa Torre; Theodora Chlapanidas
Journal:  Int J Pharm       Date:  2017-02-02       Impact factor: 5.875

4.  Soluplus micelles for acyclovir ocular delivery: Formulation and cornea and sclera permeability.

Authors:  Angela Varela-Garcia; Angel Concheiro; Carmen Alvarez-Lorenzo
Journal:  Int J Pharm       Date:  2018-09-22       Impact factor: 5.875

5.  Soluplus micelles for improving the oral bioavailability of scopoletin and their hypouricemic effect in vivo.

Authors:  Ying-Chun Zeng; Sha Li; Chang Liu; Tao Gong; Xun Sun; Yao Fu; Zhi-Rong Zhang
Journal:  Acta Pharmacol Sin       Date:  2017-01-23       Impact factor: 6.150

6.  Retentive device for intravesical drug delivery based on water-induced shape memory response of poly(vinyl alcohol): design concept and 4D printing feasibility.

Authors:  A Melocchi; N Inverardi; M Uboldi; F Baldi; A Maroni; S Pandini; F Briatico-Vangosa; L Zema; A Gazzaniga
Journal:  Int J Pharm       Date:  2019-01-30       Impact factor: 5.875

Review 7.  Polymeric oncolytic adenovirus for cancer gene therapy.

Authors:  Joung-Woo Choi; Young Sook Lee; Chae-Ok Yun; Sung Wan Kim
Journal:  J Control Release       Date:  2015-10-23       Impact factor: 9.776

8.  Margination of micro- and nano-particles in blood flow and its effect on drug delivery.

Authors:  Kathrin Müller; Dmitry A Fedosov; Gerhard Gompper
Journal:  Sci Rep       Date:  2014-05-02       Impact factor: 4.379

Review 9.  Application of hyaluronic acid as carriers in drug delivery.

Authors:  Gangliang Huang; Hualiang Huang
Journal:  Drug Deliv       Date:  2018-11       Impact factor: 6.419

10.  Chiral flavanones from Amygdalus lycioides Spach: structural elucidation and identification of TNFalpha inhibitors by bioactivity-guided fractionation.

Authors:  Raffaella Gaggeri; Daniela Rossi; Michael S Christodoulou; Daniele Passarella; Flavio Leoni; Ornella Azzolina; Simona Collina
Journal:  Molecules       Date:  2012-02-08       Impact factor: 4.411

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