Once-a-day pindolol in hypertension.

The possibility of using pindolol on a once-a-day schedule was investigated in the treatment of mild to moderate hypertension. Eighteen patients whose blood pressure responded satisfactorily to thrice-daily administration has a similar response to the single daily dose (p greater than 0.05). The advantages of once-daily pindolol therapy as well as some of the biochemical changes produced by the drug are commented upon.