A Compact Low-Power Current-to-Digital Readout Circuit for Amperometric Electrochemical Sensors.

This paper introduces a novel compact low-power amperometric instrumentation design with current-to-digital output for electrochemical sensors. By incorporating the double layer capacitance of an electrochemical sensor's impedance model, our new design can maintain performance while dramatically reducing circuit complexity and size. Electrochemical experiments with potassium ferricyanide, show that the circuit output is in good agreement with results obtained using commercial amperometric instrumentation. A high level of linearity (R2 = 0.991) between the circuit output and the concentration of potassium ferricyanide was also demonstrated. Furthermore, we show that a CMOS implementation of the presented architecture could save 25.3% of area, and 47.6% of power compared to a traditional amperometric instrumentation structure. Thus, this new circuit structure is ideally suited for portable/wireless electrochemical sensing applications.