N Bou Saleh1, T Voron2, N De'Angelis3, I Franco4,5, F Canoui-Poitrine6,7, D Mutter5, F Brunetti3, J Gagnière1, R Memeo4,5, D Pezet1, B Monange8, B Pereira9, B Le Roy10. 1. Department of Digestive Surgery, Service de Chirurgie Digestive Et Hépato-Biliaire, CHU Estaing, 2, Place Lucie Aubrac, 63000, Clermont-Ferrand, France. 2. Department of Digestive Surgery, Georges Pompidou European Hospital, Paris, France. 3. Department of Digestive Surgery, Hepato-Pancreato-Biliary Surgery, and Liver Transplantation, Henri-Mondor Hospital, AP-HP, Créteil, France. 4. Department of Emergency and Organ Transplantation, Azienda Ospedaliero-Universitaria, Bari, Italy. 5. Hepato-Biliary and Pancreatic Surgical Unit, IRCAD-IHU, University of Strasbourg, Strasbourg, France. 6. Biostatistics Department, Henri Mondor Hospital, Assistance Publique Hôpitaux de Paris, Créteil, France. 7. CEpiA EA7376, DHU Ageing-Thorax-Vessel-Blood, Université Paris Est (UPEC), Créteil, France. 8. Medical Department, Emile Roux Hospital, Puy-en-Velay, France. 9. Clinical Research and Innovation Delegation (DRCI), CHU Clermont-Ferrand, Clermont-Ferrand, France. 10. Department of Digestive Surgery, Service de Chirurgie Digestive Et Hépato-Biliaire, CHU Estaing, 2, Place Lucie Aubrac, 63000, Clermont-Ferrand, France. leroybertrand8@gmail.com.
Abstract
BACKGROUND: Laparoscopic right hemicolectomy (LRHC) is increasingly performed for the treatment of right colon disease. Nevertheless, standardization of the surgical technique regarding the performance of intracorporeal (IC) or extracorporeal (EC) anastomosis is lacking. The purpose of this study was to compare short-term postoperative outcomes in patients who had laparoscopic right colectomy either with IC or EC. METHODS: This was a retrospective, non-randomized and multicenter study conducted from January 2005 to December 2015 on the CLIMHET study group cohort from five tertiary centers in France. Data were collected for all patients with LRHC to compare patient characteristics, intraoperative data and postoperative outcomes in terms of medical and surgical complications, duration of hospitalization and mortality. A multivariate analysis was performed to compare the results in the two groups. RESULTS: Of the 597 patients undergoing LRHC, 150 had IC and 447 had EC. The incidence of medical complications (cardiac, vascular, and pulmonary complications) was lower in the IC group than in the EC group (13 vs 20%, p = 0.049). This difference remained significant in multivariate analysis after adjusting to field characteristics and patient histories (p = 0.009). Additionally, a shorter hospital stay (7 vs 8 days, p = 0.003) was observed in the IC group as compared to the EC group. This difference remained significant in favor of the IC group in multivariate analysis (p = 0.029). There was no difference between the groups as regards: surgical complications (p = 0.76), time of mobilization (p = 0.93), reintervention rate (p = 1) and 90-day mortality (p = 0.47). CONCLUSIONS: Our results show that IC anastomosis in LRHC is associated with fewer medical complications and shorter hospital stays compared to EC anastomosis.
BACKGROUND: Laparoscopic right hemicolectomy (LRHC) is increasingly performed for the treatment of right colon disease. Nevertheless, standardization of the surgical technique regarding the performance of intracorporeal (IC) or extracorporeal (EC) anastomosis is lacking. The purpose of this study was to compare short-term postoperative outcomes in patients who had laparoscopic right colectomy either with IC or EC. METHODS: This was a retrospective, non-randomized and multicenter study conducted from January 2005 to December 2015 on the CLIMHET study group cohort from five tertiary centers in France. Data were collected for all patients with LRHC to compare patient characteristics, intraoperative data and postoperative outcomes in terms of medical and surgical complications, duration of hospitalization and mortality. A multivariate analysis was performed to compare the results in the two groups. RESULTS: Of the 597 patients undergoing LRHC, 150 had IC and 447 had EC. The incidence of medical complications (cardiac, vascular, and pulmonary complications) was lower in the IC group than in the EC group (13 vs 20%, p = 0.049). This difference remained significant in multivariate analysis after adjusting to field characteristics and patient histories (p = 0.009). Additionally, a shorter hospital stay (7 vs 8 days, p = 0.003) was observed in the IC group as compared to the EC group. This difference remained significant in favor of the IC group in multivariate analysis (p = 0.029). There was no difference between the groups as regards: surgical complications (p = 0.76), time of mobilization (p = 0.93), reintervention rate (p = 1) and 90-day mortality (p = 0.47). CONCLUSIONS: Our results show that IC anastomosis in LRHC is associated with fewer medical complications and shorter hospital stays compared to EC anastomosis.
Authors: Marco Milone; Antonella Desiderio; Nunzio Velotti; Michele Manigrasso; Sara Vertaldi; Umberto Bracale; Michele D'Ambra; Giuseppe Servillo; Giuseppe De Simone; Fatima Domenica Elisa De Palma; Giuseppe Perruolo; Gregory Alexander Raciti; Claudia Miele; Francesco Beguinot; Giovanni Domenico De Palma Journal: Sci Rep Date: 2021-05-06 Impact factor: 4.379