| Literature DB >> 32291561 |
Getinet Ayano1, Kim Betts2, Joemer Calderon Maravilla3, Rosa Alati2,3.
Abstract
Inconsistent results of the association between severe psychiatric disorders (SPD) in parents and the risk of disruptive behavioral disorders (DBD) including conduct disorders (CD) and oppositional defiant disorders (ODD) in the offspring have been found by previous epidemiologic studies. PubMed, EMBASE, PsycINFO, and Scopus were searched for relevant studies. Fourteen studies met the predefined criteria for inclusion. A meta-analysis of the included studies revealed an elevated risk of DBD in the offspring of parents with SPD, bipolar, and depressive disorders. Our further analysis considering the specific DBD as an outcome showed that parents with SPD are at an increased risk of having a child with ODD as well as CD. Moreover, the current meta-analysis found that the children of parents with bipolar disorder were also at increased risk of ODD and CD. Parental schizophrenia and depressive disorders were not associated with higher risks of ODD and CD in the offspring.Entities:
Keywords: Disruptive behavioral disorder; offspring; Parent; Severe psychiatric disorder; Systematic review
Mesh：
Year: 2021 PMID： 32291561 DOI： 10.1007/s10578-020-00989-4
Source DB: PubMed Journal: Child Psychiatry Hum Dev ISSN： 0009-398X