Literature DB >> 3229030

Assessment of cognitive function in elderly patients treated with naproxen. A prospective study.

A J Wysenbeek1, Z Klein, S Nakar, R Mane.   

Abstract

Cognitive functions were assessed in 12 elderly patients prior to and following a three-week therapeutic course of Naproxen, 750 mg/day. Four of the patients deteriorated in one of the four cognitive tests, one of these patients in two tests. However, none of these changes reached statistical significance. Although non-steroidal anti-inflammatory drugs can cause some cognitive alteration in the elderly, this change is mild, and its clinical meaning questioned.

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Year:  1988        PMID： 3229030

Source DB:  PubMed          Journal:  Clin Exp Rheumatol        ISSN： 0392-856X            Impact factor:   4.473


  5 in total

Review 1.  Drug-induced cognition disorders in the elderly: incidence, prevention and management.

Authors:  S L Gray; K V Lai; E B Larson
Journal:  Drug Saf       Date:  1999-08       Impact factor: 5.606

Review 2.  Nonsteroidal anti-inflammatory drugs and cognitive function: do they have a beneficial or deleterious effect?

Authors:  T M Karplus; K G Saag
Journal:  Drug Saf       Date:  1998-12       Impact factor: 5.606

3.  CNS Adverse Effects of Nonsteroidal Anti-Inflammatory Drugs : Therapeutic Implications.

Authors:  A Morgan; D Clark
Journal:  CNS Drugs       Date:  1998-04       Impact factor: 5.749

Review 4.  Rheumatoid arthritis in the aged. Incidence and optimal management.

Authors:  G Nesher; T L Moore
Journal:  Drugs Aging       Date:  1993 Nov-Dec       Impact factor: 3.923

5.  Indomethacin and cognitive function in healthy elderly volunteers.

Authors:  P N Bruce-Jones; P Crome; L Kalra
Journal:  Br J Clin Pharmacol       Date:  1994-07       Impact factor: 4.335
  5 in total

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