| Literature DB >> 32289858 |
Elisa d'Alessandro1, Christian Becker2, Wolfgang Bergmeier3, Christoph Bode4, Joshua H Bourne5, Helena Brown6, Harry R Buller7, Arina J Ten Cate-Hoek1, Vincent Ten Cate8, Yvonne J M van Cauteren9, Yam F H Cheung10, Audrey Cleuren11, Danielle Coenen12, Harry J G M Crijns9, Ilaria de Simone12, Sophie C Dolleman13, Christine Espinola Klein14, Delia I Fernandez12, Lianne Granneman15, Arnoud van T Hof9, Peter Henke16, Yvonne M C Henskens17, Jingnan Huang12, Lisa K Jennings18, Natalie Jooss12, Mieke Karel12, Danique van den Kerkhof12, Frederik A Klok19, Bram Kremers1, Bernhard Lämmle20, Avi Leader1,21, Annika Lundstrom22, Nigel Mackman23, Pier M Mannucci24, Zahra Maqsood6, Paola E J van der Meijden1,12, Marc van Moorsel15, Luis A Moran25, John Morser26, Manouk van Mourik9, Stefano Navarro6, Raluca A I Neagoe5, Renske H Olie1, Pauline van Paridon1, Jens Posma1, Isabella Provenzale12, Pieter H Reitsma13, Billy Scaf1, Leon Schurgers12, Jaap Seelig1,27, Agneta Siegbahn28, Bob Siegerink29, Oliver Soehnlein30, Eva Maria Soriano31, Marcin A Sowa31, Henri M H Spronk1, Robert F Storey32, Chukiat Tantiwong12, Alicia Veninga12, Xueqing Wang5, Steve P Watson5, Jeff Weitz33, Sacha S Zeerleder34, Hugo Ten Cate1.
Abstract
Thrombo-inflammation describes the complex interplay between blood coagulation and inflammation that plays a critical role in cardiovascular diseases. The third Maastricht Consensus Conference on Thrombosis assembled basic, translational, and clinical scientists to discuss the origin and potential consequences of thrombo-inflammation in the etiology, diagnostics, and management of patients with cardiovascular disease, including myocardial infarction, stroke, and peripheral artery disease. This article presents a state-of-the-art reflection of expert opinions and consensus recommendations regarding the following topics: (1) challenges of the endothelial cell barrier; (2) circulating cells and thrombo-inflammation, focused on platelets, neutrophils, and neutrophil extracellular traps; (3) procoagulant mechanisms; (4) arterial vascular changes in atherogenesis; attenuating atherosclerosis and ischemia/reperfusion injury; (5) management of patients with arterial vascular disease; and (6) pathogenesis of venous thrombosis and late consequences of venous thromboembolism. Georg Thieme Verlag KG Stuttgart · New York.Entities:
Mesh：
Year: 2020 PMID： 32289858 DOI： 10.1055/s-0040-1708035
Source DB: PubMed Journal: Thromb Haemost ISSN： 0340-6245 Impact factor: 5.249