| Literature DB >> 322894 |
T F Davies, A Gomez-Pan, M J Watson, C Q Mountjoy, J P Hanker, G M Besser, R Hall.
Abstract
Ten endocrinologically normal men with secondary sexual impotence were given 500 microng LHRH subcutaneously every 8 h. After 4 weeks treatment the LH response to 500 microng LHRH was reduced from a peak of 35.7+/-5.2 to 16.8+/-3.5 mu/ml (P less than 0.01) and the FSH response from 4.2+/-0.93 to 2.39+/-0.4 mu/ml (P greater than 0.01). Circulating total testosterone, oestradiol, prolactin and sex hormone binding globulin showed no significant changes. Whether this inability of the pituitary to maintain it s response to LHRH is peculiar to impotent men requires further study.Entities:
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Year: 1977 PMID： 322894 DOI： 10.1111/j.1365-2265.1977.tb03317.x
Source DB: PubMed Journal: Clin Endocrinol (Oxf) ISSN： 0300-0664 Impact factor: 3.478