| Literature DB >> 32285417 |
Tarik Smani1,2, Isabel Mayoral-Gonzalez3,4, Isabel Galeano-Otero3, Isabel Gallardo-Castillo5, Juan A Rosado6, Antonio Ordoñez3,4,7, Abdelkrim Hmadcha8.
Abstract
The Ischemic Heart Disease (IHD) is considered a clinical condition characterized by myocardial ischemia causing an imbalance between myocardial blood supply and demand, leading to morbidity and mortality across the worldwide. Prompt diagnostic and prognostic represents key factors for the treatment and reduction of the mortality rate. Therefore, one of the newest frontiers in cardiovascular research is related to non-coding RNAs (ncRNAs), which prompted a huge interest in exploring ncRNAs candidates for utilization as potential therapeutic targets for diagnostic and prognostic and/or biomarkers in IHD. However, there are undoubtedly many more functional ncRNAs yet to be discovered and characterized. Here we will discuss our current knowledge and we will provide insight on the roles and effects elicited by some ncRNAs related to IHD.Entities:
Keywords: Cardioprotection; Ischemia and reperfusion; Non-coding RNAs; RNAs
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Year: 2020 PMID： 32285417 DOI： 10.1007/978-981-15-1671-9_15
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622