Literature DB >> 32285072

The essential role of osteoclast-derived exosomes in magnetic nanoparticle-infiltrated hydroxyapatite scaffold modulated osteoblast proliferation in an osteoporosis model.

Yue Zhu1, Zhiyu Li, Yujia Zhang, Fang Lan, Jing He, Yao Wu.   

Abstract

Magnetic hydroxyapatite (MHA) scaffolds promoted osteoblast proliferation in a model of osteoporosis through altering the osteoclast-derived exosomal cargo and decreasing the efficiency of exosome uptake by osteoblasts. Noticeably, certain proteins including ubiquitin, ATP and reactive oxygen species decreased in the osteoclast-derived exosomal cargo with MHA stimulation, while Rho kinase increased.

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Year:  2020        PMID： 32285072     DOI： 10.1039/d0nr00867b

Source DB:  PubMed          Journal:  Nanoscale        ISSN： 2040-3364            Impact factor:   7.790


  13 in total

1.  Research progress on effect of magnetic nanoparticle composite scaffold on osteogenesis.

Authors:  Wenni Wang; Chaoqun Chen; Xinhua Gu
Journal:  Zhejiang Da Xue Xue Bao Yi Xue Ban       Date:  2022-02-25

Review 2.  Harnessing the Therapeutic Potential of Extracellular Vesicles for Biomedical Applications Using Multifunctional Magnetic Nanomaterials.

Authors:  Letao Yang; Kapil D Patel; Christopher Rathnam; Ramar Thangam; Yannan Hou; Heemin Kang; Ki-Bum Lee
Journal:  Small       Date:  2022-02-08       Impact factor: 15.153

3.  Ferric Ion Induction of Triggering Receptor Expressed in Myeloid Cells-2 Expression and PI3K/Akt Signaling Pathway in Preosteoclast Cells to Promote Osteoclast Differentiation.

Authors:  Lu-Lin Liu; Zi-Hou Cao; Chun-Lei He; Yan-Chun Zhong; Wu-Yang Liu; Peng Zhang; Fan Yang; You-Jia Xu
Journal:  Orthop Surg       Date:  2020-07-30       Impact factor: 2.071

Review 4.  Paramagnetic Functionalization of Biocompatible Scaffolds for Biomedical Applications: A Perspective.

Authors:  Simona Bettini; Valentina Bonfrate; Ludovico Valli; Gabriele Giancane
Journal:  Bioengineering (Basel)       Date:  2020-11-28

Review 5.  Bioactive Scaffolds Integrated with Liposomal or Extracellular Vesicles for Bone Regeneration.

Authors:  Minjee Kang; Chung-Sung Lee; Min Lee
Journal:  Bioengineering (Basel)       Date:  2021-10-01

6.  Integration of Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanisms of Zhuanggu Busui Formula Against Osteoporosis.

Authors:  Huihao Zhang; Chengcong Zhou; Zhiguo Zhang; Sai Yao; Yishan Bian; Fangda Fu; Huan Luo; Yan Li; Shuxin Yan; Yuying Ge; Yuying Chen; Kunyu Zhan; Ming Yue; Weibin Du; Kun Tian; Hongting Jin; Xiaofeng Li; Peijian Tong; Hongfeng Ruan; Chengliang Wu
Journal:  Front Endocrinol (Lausanne)       Date:  2022-01-28       Impact factor: 5.555

Review 7.  Therapeutic Treatments for Osteoporosis-Which Combination of Pills Is the Best among the Bad?

Authors:  Christian Horst Tonk; Sarah Hani Shoushrah; Patrick Babczyk; Basma El Khaldi-Hansen; Margit Schulze; Monika Herten; Edda Tobiasch
Journal:  Int J Mol Sci       Date:  2022-01-26       Impact factor: 5.923

8.  Bone mesenchymal stem cells stimulation by magnetic nanoparticles and a static magnetic field: release of exosomal miR-1260a improves osteogenesis and angiogenesis.

Authors:  Di Wu; Xiao Chang; Jingjing Tian; Lin Kang; Yuanhao Wu; Jieying Liu; Xiangdong Wu; Yue Huang; Bo Gao; Hai Wang; Guixing Qiu; Zhihong Wu
Journal:  J Nanobiotechnology       Date:  2021-07-13       Impact factor: 10.435

Review 9.  Exosomes as a Novel Approach to Reverse Osteoporosis: A Review of the Literature.

Authors:  Xudong Xie; Yuan Xiong; Adriana C Panayi; Liangcong Hu; Wu Zhou; Hang Xue; Ze Lin; Lang Chen; Chenchen Yan; Bobin Mi; Guohui Liu
Journal:  Front Bioeng Biotechnol       Date:  2020-10-23

Review 10.  Exosomes: A Friend or Foe for Osteoporotic Fracture?

Authors:  Zhimin Yang; Wenchao Zhang; Xiaolei Ren; Chao Tu; Zhihong Li
Journal:  Front Endocrinol (Lausanne)       Date:  2021-06-21       Impact factor: 5.555
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