Guyu Huang1, Qianqian Huang1, Guoqiang Zhang1, Hu Jiang1, Zhen Lin2. 1. Department of Hospital Infection Prevention and Control, Affiliated Cancer Hospital of Guangxi Medical University, Nanning, China. 2. Department of Hospital Infection Prevention and Control, Affiliated Cancer Hospital of Guangxi Medical University, Nanning, China. Electronic address: zhenlin2019@163.com.
Abstract
BACKGROUND: Both hospital-acquired infection (HAI) and cancer represents major health concerns worldwide, but there is a paucity of data describing HAI in Chinese cancer patients. The objective of this study is to demonstrate the prevalence, causative agents, antimicrobial use and risk factors for HAI in a cancer hospital in Southwestern China. METHODS: We use the criteria of the Ministry of Health of the People's Republic of China to define hospital-acquired infections. One-day cross-sectional surveys were annually conducted from 2014 to 2018. Trained staff collected hospital-acquired infections, antimicrobial use and clinical characteristics data of inpatients. Multivariate logistic regression was used to determine the potential risk factors associated with HAIs. RESULTS: Of the 6717 patients surveyed, there were 140 patients (2.1%, 95% confidence interval, 1.7-2.4%) with 144 distinct HAIs. Lower respiratory tract infections (47, 32.6%) and surgical-site infections (29, 20.1%) were the most common HAIs. Escherichia coli was the most common pathogen (29.6%). Risk factors for HAI included younger age (<18 years) or older age (>65 years), hospitalization in the intensive care unit, presence of central catheter and undergoing surgery in the previous 30 days. The overall prevalence of patients receiving antimicrobial agents was 15.2%. CONCLUSION: To control hospital-acquired infections in cancer patients, surveillance and prevention strategies to infections associated with central catheters or related to surgery should be augmented.
BACKGROUND: Both hospital-acquired infection (HAI) and cancer represents major health concerns worldwide, but there is a paucity of data describing HAI in Chinese cancerpatients. The objective of this study is to demonstrate the prevalence, causative agents, antimicrobial use and risk factors for HAI in a cancer hospital in Southwestern China. METHODS: We use the criteria of the Ministry of Health of the People's Republic of China to define hospital-acquired infections. One-day cross-sectional surveys were annually conducted from 2014 to 2018. Trained staff collected hospital-acquired infections, antimicrobial use and clinical characteristics data of inpatients. Multivariate logistic regression was used to determine the potential risk factors associated with HAIs. RESULTS: Of the 6717 patients surveyed, there were 140 patients (2.1%, 95% confidence interval, 1.7-2.4%) with 144 distinct HAIs. Lower respiratory tract infections (47, 32.6%) and surgical-site infections (29, 20.1%) were the most common HAIs. Escherichia coli was the most common pathogen (29.6%). Risk factors for HAI included younger age (<18 years) or older age (>65 years), hospitalization in the intensive care unit, presence of central catheter and undergoing surgery in the previous 30 days. The overall prevalence of patients receiving antimicrobial agents was 15.2%. CONCLUSION: To control hospital-acquired infections in cancerpatients, surveillance and prevention strategies to infections associated with central catheters or related to surgery should be augmented.
Authors: Bianca Tabita Muresan; Martín Núñez-Abad; Ana Artero; Jaime Rios Rios; Alberto Jacobo Cunquero-Tomás; Vega Iranzo; Javier Garrido; Ana Jiménez-Portilla; Carlos Camps Herrero; Carlos J Sánchez Juan Journal: J Nutr Metab Date: 2022-08-16