Kun Yuan1, Haoyuan Wang2, Yujia Chen2, Sijie Li2, Qiang Wang3, Yanmin Cao4, Shuqing Gao5, Xiaoli Xu6, Qi Xie7. 1. Nursing Department, The Fourth Hospital of Shijiazhuang, Shijiazhuang 050011, China. 2. School of Basic Medical Sciences, Hebei Medical University, Shijiazhuang 050017, China. 3. Department of Thoracic Surgery, The First Hospital of Hebei Medical University, Shijiazhuang 050000, China. 4. Emergency Department, The Fourth Hospital of Shijiazhuang, Shijiazhuang 050011, China. 5. Department of Nutrition, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China. 6. Medical Record Department, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China. 7. Department of Nutrition, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China. w1420174542@126.com.
Abstract
BACKGROUND:Gestational diabetes mellitus (GDM) is associated with adverse outcomes and neonatal complications. Its prevalence has been rapidly increasing over the last decade; it is estimated that one in six pregnant women are diagnosed with GDM. Thus, an effective management approach is necessary for women with GDM. This study investigated the effect of a 12-h comprehensive nutrition care (12h-HNC) on the metabolism and outcomes of pregnant women with GDM and neonatal birth weight and hypoglycemia. METHODS: The study included 312 pregnant women with GDM at 24-28 weeks of gestation who were treated in our department from January 2014 to December 2016. They were randomly assigned to receive a 12h-HNC (12h-HNC group, n=158) or traditional one-time nutrition guidance (control group, n=154). Maternal blood glucose levels and weight gain, as well as maternal and neonatal outcomes were evaluated and compared between the groups. RESULTS: Compared to those in the control group, patients in the 12h-HNC group had significantly lower 2-h postprandial glucose levels (P<0.05), lower average weight increase (P<0.05), and better outcomes (P<0.05). Neonatal birth weight and incidence of macrosomia were significantly lower in the 12h-HNC group. The incidence of cesarean section was similar in the two groups (P>0.05). CONCLUSIONS: The 12h-HNC enabled better blood glucose and weight increase control, improving both maternal and neonatal outcomes in women with GDM. This comprehensive nutrition intervention may achieve favorable effects in clinical practice.
RCT Entities:
BACKGROUND:Gestational diabetes mellitus (GDM) is associated with adverse outcomes and neonatal complications. Its prevalence has been rapidly increasing over the last decade; it is estimated that one in six pregnant women are diagnosed with GDM. Thus, an effective management approach is necessary for women with GDM. This study investigated the effect of a 12-h comprehensive nutrition care (12h-HNC) on the metabolism and outcomes of pregnant women with GDM and neonatal birth weight and hypoglycemia. METHODS: The study included 312 pregnant women with GDM at 24-28 weeks of gestation who were treated in our department from January 2014 to December 2016. They were randomly assigned to receive a 12h-HNC (12h-HNC group, n=158) or traditional one-time nutrition guidance (control group, n=154). Maternal blood glucose levels and weight gain, as well as maternal and neonatal outcomes were evaluated and compared between the groups. RESULTS: Compared to those in the control group, patients in the 12h-HNC group had significantly lower 2-h postprandial glucose levels (P<0.05), lower average weight increase (P<0.05), and better outcomes (P<0.05). Neonatal birth weight and incidence of macrosomia were significantly lower in the 12h-HNC group. The incidence of cesarean section was similar in the two groups (P>0.05). CONCLUSIONS: The 12h-HNC enabled better blood glucose and weight increase control, improving both maternal and neonatal outcomes in women with GDM. This comprehensive nutrition intervention may achieve favorable effects in clinical practice.