Literature DB >> 32279361

To kidney or not to kidney: Applying lessons learned from the simultaneous liver-kidney transplant policy to simultaneous heart-kidney transplantation.

Xingxing S Cheng1, Kiran K Khush2, Alexander Wiseman3, Jeffrey Teuteberg2, Jane C Tan1.   

Abstract

As the medical community is increasingly offering transplantation to patients with increasing comorbidity burdens, the number of simultaneous heart-kidney (SHK) transplants is rising in the United States. How to determine eligibility for SHK transplant versus heart transplant alone is unknown. In this review, we situate this problem in the broader picture of organ shortage. We critically appraise available literature on outcomes in SHK versus heart transplant alone. We posit staged kidney-after-heart transplantation as a plausible alternative to SHK transplantation and review the pros and cons. Drawing lessons from the field of simultaneous liver-kidney transplant, we argue for an analogous policy for SHK transplant with standardized minimal eligibility criteria and a modified Safety Net provision. The new policy will serve as a starting point for comparing simultaneous versus staged approaches and refining the medical eligibility criteria for SHK.
© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  allocation; heart transplant; heart-kidney transplant; kidney transplant; liver transplant; liver-kidney transplant; policy

Mesh:

Year:  2020        PMID: 32279361     DOI: 10.1111/ctr.13878

Source DB:  PubMed          Journal:  Clin Transplant        ISSN: 0902-0063            Impact factor:   2.863


  4 in total

1.  Optimal patient selection for simultaneous heart-kidney transplant: A modified cost-effectiveness analysis.

Authors:  Brian Wayda; Xingxing S Cheng; Jeremy D Goldhaber-Fiebert; Kiran K Khush
Journal:  Am J Transplant       Date:  2021-11-30       Impact factor: 8.086

2.  Need for improvements in simultaneous heart-kidney allocation: The limitation of pretransplant glomerular filtration rate.

Authors:  Brian I Shaw; Mariya L Samoylova; Scott Sanoff; Andrew S Barbas; Debra L Sudan; L Ebony Boulware; Lisa M McElroy
Journal:  Am J Transplant       Date:  2021-02-09       Impact factor: 9.369

3.  And Then There Were Three: Effects of Pretransplant Dialysis on Multiorgan Transplantation.

Authors:  Xingxing S Cheng; Jialin Han; Margaret R Stedman; Glenn M Chertow; Jane C Tan
Journal:  Transplant Direct       Date:  2021-01-15

Review 4.  Combined Heart-Kidney Transplantation: Indications, Outcomes, and Controversies.

Authors:  Syed Adeel Ahsan; Ashrith Guha; Juan Gonzalez; Arvind Bhimaraj
Journal:  Methodist Debakey Cardiovasc J       Date:  2022-09-06
  4 in total

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