Literature DB >> 32277815

The Clofazimine for Treatment of Cryptosporidiosis in HIV-Infected Adults (CRYPTOFAZ) and Lessons Learned for Anticryptosporidial Drug Development.

Christopher D Huston1,2.   

Abstract

Entities:  

Keywords:  anticryptosporidial; clofazimine; controlled human infection model; cryptosporidiosis; cryptosporidium

Mesh：

Substances：

Year:  2021        PMID： 32277815      PMCID： PMC8427724          DOI： 10.1093/cid/ciaa425

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


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  12 in total

Review 1.  Prevention and treatment of cryptosporidiosis in immunocompromised patients.

Authors:  I Abubakar; S H Aliyu; C Arumugam; P R Hunter; N K Usman
Journal:  Cochrane Database Syst Rev       Date:  2007-01-24

Review 2.  A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium.

Authors:  William Checkley; A Clinton White; Devan Jaganath; Michael J Arrowood; Rachel M Chalmers; Xian-Ming Chen; Ronald Fayer; Jeffrey K Griffiths; Richard L Guerrant; Lizbeth Hedstrom; Christopher D Huston; Karen L Kotloff; Gagandeep Kang; Jan R Mead; Mark Miller; William A Petri; Jeffrey W Priest; David S Roos; Boris Striepen; R C Andrew Thompson; Honorine D Ward; Wesley A Van Voorhis; Lihua Xiao; Guan Zhu; Eric R Houpt
Journal:  Lancet Infect Dis       Date:  2014-09-29       Impact factor: 25.071

3.  The infectivity of Cryptosporidium parvum in healthy volunteers.

Authors:  H L DuPont; C L Chappell; C R Sterling; P C Okhuysen; J B Rose; W Jakubowski
Journal:  N Engl J Med       Date:  1995-03-30       Impact factor: 91.245

Review 4.  Cryptosporidiosis Drug Discovery: Opportunities and Challenges.

Authors:  Ujjini H Manjunatha; Alexander T Chao; F Joel Leong; Thierry T Diagana
Journal:  ACS Infect Dis       Date:  2016-07-22       Impact factor: 5.084

5.  Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study.

Authors:  Karen L Kotloff; James P Nataro; William C Blackwelder; Dilruba Nasrin; Tamer H Farag; Sandra Panchalingam; Yukun Wu; Samba O Sow; Dipika Sur; Robert F Breiman; Abu Sg Faruque; Anita Km Zaidi; Debasish Saha; Pedro L Alonso; Boubou Tamboura; Doh Sanogo; Uma Onwuchekwa; Byomkesh Manna; Thandavarayan Ramamurthy; Suman Kanungo; John B Ochieng; Richard Omore; Joseph O Oundo; Anowar Hossain; Sumon K Das; Shahnawaz Ahmed; Shahida Qureshi; Farheen Quadri; Richard A Adegbola; Martin Antonio; M Jahangir Hossain; Adebayo Akinsola; Inacio Mandomando; Tacilta Nhampossa; Sozinho Acácio; Kousick Biswas; Ciara E O'Reilly; Eric D Mintz; Lynette Y Berkeley; Khitam Muhsen; Halvor Sommerfelt; Roy M Robins-Browne; Myron M Levine
Journal:  Lancet       Date:  2013-05-14       Impact factor: 79.321

6.  Clofazimine for Treatment of Cryptosporidiosis in Human Immunodeficiency Virus Infected Adults: An Experimental Medicine, Randomized, Double-blind, Placebo-controlled Phase 2a Trial.

Authors:  Py Iroh Tam; S L M Arnold; L K Barrett; C R Chen; T M Conrad; E Douglas; M A Gordon; D Hebert; M Henrion; D Hermann; B Hollingsworth; E Houpt; K C Jere; R Lindblad; M S Love; L Makhaza; C W McNamara; W Nedi; J Nyirenda; D J Operario; J Phulusa; G V Quinnan; L A Sawyer; H Thole; N Toto; A Winter; W C Van Voorhis
Journal:  Clin Infect Dis       Date:  2021-07-15       Impact factor: 9.079

7.  A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis.

Authors:  Melissa S Love; Federico C Beasley; Rajiv S Jumani; Timothy M Wright; Arnab K Chatterjee; Christopher D Huston; Peter G Schultz; Case W McNamara
Journal:  PLoS Negl Trop Dis       Date:  2017-02-03

8.  Epidemiology and Risk Factors for Cryptosporidiosis in Children From 8 Low-income Sites: Results From the MAL-ED Study.

Authors:  Poonum S Korpe; Cristian Valencia; Rashidul Haque; Mustafa Mahfuz; Monica McGrath; Eric Houpt; Margaret Kosek; Benjamin J J McCormick; Pablo Penataro Yori; Sudhir Babji; Gagandeep Kang; Dennis Lang; Michael Gottlieb; Amidou Samie; Pascal Bessong; A S G Faruque; Esto Mduma; Rosemary Nshama; Alexandre Havt; Ila F N Lima; Aldo A M Lima; Ladaporn Bodhidatta; Ashish Shreshtha; William A Petri; Tahmeed Ahmed; Priya Duggal
Journal:  Clin Infect Dis       Date:  2018-11-13       Impact factor: 9.079

9.  A Proposed Target Product Profile and Developmental Cascade for New Cryptosporidiosis Treatments.

Authors:  Christopher D Huston; Thomas Spangenberg; Jeremy Burrows; Paul Willis; Timothy N C Wells; Wesley van Voorhis
Journal:  PLoS Negl Trop Dis       Date:  2015-10-08

10.  Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control study.

Authors:  Jie Liu; James A Platts-Mills; Jane Juma; Furqan Kabir; Joseph Nkeze; Catherine Okoi; Darwin J Operario; Jashim Uddin; Shahnawaz Ahmed; Pedro L Alonso; Martin Antonio; Stephen M Becker; William C Blackwelder; Robert F Breiman; Abu S G Faruque; Barry Fields; Jean Gratz; Rashidul Haque; Anowar Hossain; M Jahangir Hossain; Sheikh Jarju; Farah Qamar; Najeeha Talat Iqbal; Brenda Kwambana; Inacio Mandomando; Timothy L McMurry; Caroline Ochieng; John B Ochieng; Melvin Ochieng; Clayton Onyango; Sandra Panchalingam; Adil Kalam; Fatima Aziz; Shahida Qureshi; Thandavarayan Ramamurthy; James H Roberts; Debasish Saha; Samba O Sow; Suzanne E Stroup; Dipika Sur; Boubou Tamboura; Mami Taniuchi; Sharon M Tennant; Deanna Toema; Yukun Wu; Anita Zaidi; James P Nataro; Karen L Kotloff; Myron M Levine; Eric R Houpt
Journal:  Lancet       Date:  2016-09-24       Impact factor: 79.321
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  3 in total

1.  A genetic screen identifies a protective type III interferon response to Cryptosporidium that requires TLR3 dependent recognition.

Authors:  Alexis R Gibson; Adam Sateriale; Jennifer E Dumaine; Julie B Engiles; Ryan D Pardy; Jodi A Gullicksrud; Keenan M O'Dea; John G Doench; Daniel P Beiting; Christopher A Hunter; Boris Striepen
Journal:  PLoS Pathog       Date:  2022-05-18       Impact factor: 7.464

Review 2.  An Overview of Mucosa-Associated Protozoa: Challenges in Chemotherapy and Future Perspectives.

Authors:  Helena Lucia Carneiro Santos; Karina M Rebello
Journal:  Front Cell Infect Microbiol       Date:  2022-04-25       Impact factor: 6.073

Review 3.  Emerging treatment options for cryptosporidiosis.

Authors:  Melissa S Love; Robert K M Choy
Journal:  Curr Opin Infect Dis       Date:  2021-10-01       Impact factor: 4.968
  3 in total

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