Literature DB >> 32277678

Minimally invasive esophagectomy for esophageal cancer in octogenarians. Clinical and oncological outcomes.

Elias Sdralis1, Spyridon Davakis, Athanasios Syllaios, Eustratia Mpaili, Bruno Lorenzi, Alexandros Charalabopoulos.   

Abstract

PURPOSE: Studies on patients undergoing esophagectomy for esophageal cancer have shown that thoracic and abdominal surgery may be performed safely in patients without an uppermost age cut-off. The aim of this study was to evaluate the morbidity and mortality of radical minimally invasive esophagectomy for cancer in patients over 80 years old.
METHODS: A retrospective analysis of prospectively collected data over a period of 4 years was conducted. During the study period 184 esophagectomies were performed. A total of 12 octogenarians that underwent Minimally Invasive Esophagectomy (MIE) for cancer were included in the study. Our results were compared to the UK national outcomes as presented in the National Esophago-Gastric Cancer Audit (NOGCA) 2017 report.
RESULTS: Median overall survival (OS) was 16.5 months (range: 6-38) and progression-free survival (PFS) 14.5 months (tange:3-38). 30-and 90-day postoperative mortality was zero. Postoperative complications included chest infection (CI) in 4 (33.3%) patients, anastomotic leakage (AL) in 3 (25%) and atrial fibrillation in 2 (16.7%).
CONCLUSIONS: MIE should therefore be considered as an effective treatment strategy even in elderly patients over 80 years of age.

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Year:  2020        PMID: 32277678

Source DB:  PubMed          Journal:  J BUON        ISSN: 1107-0625            Impact factor:   2.533


  1 in total

1.  Associations of Changes in Intestinal Flora and Inflammatory Factors with Prognosis of Patients with Esophageal Cancer.

Authors:  Cheng Wu; Ming Wang; Qing Zhou; Hui Shi
Journal:  J Healthc Eng       Date:  2022-03-27       Impact factor: 2.682

  1 in total

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