Vivien Marasigan1, Ivan Perry2, Kathleen Bennett3, Kevin Balanda4, Simon Capewell5, Martin O' Flaherty5, Zubair Kabir6. 1. School of Public Health, University College Cork, Cork, Ireland; Department of Dermatology, University Hospitals Leuven, Belgium; Department of Dermatology, University Hospital Limerick, Limerick, Ireland. 2. School of Public Health, University College Cork, Cork, Ireland. 3. Population Health Sciences Division, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland. 4. School of Public Health, University College Cork, Cork, Ireland; Institute of Public Health, Dublin, Ireland. 5. Department of Public Health and Policy, University of Liverpool, Liverpool, United Kingdom. 6. School of Public Health, University College Cork, Cork, Ireland. Electronic address: z.kabir@ucc.ie.
Abstract
BACKGROUND: To investigate the contribution of individual and population factors to Coronary Heart Disease (CHD) mortality rates in Ireland between 2000 and 2015. METHODS: The Irish IMPACT CHD model was utilized with CHD Deaths Prevented or Postponed (DPPs) as outcome. RESULTS: CHD mortality rates in Ireland in those aged 25-84 years fell by 56% (63% in women vs. men 53%), with 4060 fewer deaths than expected in 2015. Improvements in CHD risk factors explained ~30% of the decline (785 DPPs in men; 425 in women): [population systolic blood pressure (+25% DPPs), mean cholesterol serum levels (+11%) and smoking prevalence (+5%)]. Additional deaths attributable to rises in diabetes prevalence (-6%), BMI (-4%) and physical inactivity (-2%) negatively impacted DPPs. Increased uptake of cardiology treatments explained ~60% of the decline (1620 DPPs in men; 825 in women), particularly secondary prevention and heart failure treatments. Some 10% was unexplained. CONCLUSION: CHD mortality declined in Ireland between 2000 and 2015, with two-thirds attributable to increased uptake in cardiology treatments and only one-third to improvements in population risk factors, partly reflecting adverse trends in obesity, diabetes and physical inactivity. Additional investments in prevention policies and treatments will be necessary to reduce future CHD deaths.
BACKGROUND: To investigate the contribution of individual and population factors to Coronary Heart Disease (CHD) mortality rates in Ireland between 2000 and 2015. METHODS: The Irish IMPACT CHD model was utilized with CHDDeaths Prevented or Postponed (DPPs) as outcome. RESULTS:CHDmortality rates in Ireland in those aged 25-84 years fell by 56% (63% in women vs. men 53%), with 4060 fewer deaths than expected in 2015. Improvements in CHD risk factors explained ~30% of the decline (785 DPPs in men; 425 in women): [population systolic blood pressure (+25% DPPs), mean cholesterol serum levels (+11%) and smoking prevalence (+5%)]. Additional deaths attributable to rises in diabetes prevalence (-6%), BMI (-4%) and physical inactivity (-2%) negatively impacted DPPs. Increased uptake of cardiology treatments explained ~60% of the decline (1620 DPPs in men; 825 in women), particularly secondary prevention and heart failure treatments. Some 10% was unexplained. CONCLUSION:CHDmortality declined in Ireland between 2000 and 2015, with two-thirds attributable to increased uptake in cardiology treatments and only one-third to improvements in population risk factors, partly reflecting adverse trends in obesity, diabetes and physical inactivity. Additional investments in prevention policies and treatments will be necessary to reduce future CHDdeaths.
Authors: Nick Townsend; Denis Kazakiewicz; F Lucy Wright; Adam Timmis; Radu Huculeci; Aleksandra Torbica; Chris P Gale; Stephan Achenbach; Franz Weidinger; Panos Vardas Journal: Nat Rev Cardiol Date: 2021-09-08 Impact factor: 32.419
Authors: Ingrid Maria Novais Barros de Carvalho Costa; Danielle Góes da Silva; Joselina Luzia Meneses Oliveira; José Rodrigo Santos Silva; Fabrício Anjos de Andrade; Juliana de Góes Jorge; Larissa Marina Santana Mendonça de Oliveira; Rebeca Rocha de Almeida; Victor Batista Oliveira; Larissa Santos Martins; Jamille Oliveira Costa; Márcia Ferreira Cândido de Souza; Larissa Monteiro Costa Pereira; Luciana Vieira Sousa Alves; Silvia Maria Voci; Marcos Antonio Almeida-Santos; Felipe J Aidar; Leonardo Baumworcel; Antônio Carlos Sobral Sousa Journal: Clin Pract Date: 2022-07-08
Authors: Ingrid Maria Novais Barros de Carvalho Costa; Danielle Góes da Silva; Joselina Luzia Meneses Oliveira; José Rodrigo Santos Silva; Larissa Monteiro Costa Pereira; Luciana Vieira Sousa Alves; Fabrício Anjos de Andrade; Juliana de Góes Jorge; Larissa Marina Santana Mendonça de Oliveira; Rebeca Rocha de Almeida; Victor Batista Oliveira; Larissa Santos Martins; Jamille Oliveira Costa; Márcia Ferreira Cândido de Souza; Silvia Maria Voci; Marcos Antonio Almeida-Santos; Victoria Vieira Abreu; Felipe J Aidar; Leonardo Baumworcel; Antônio Carlos Sobral Sousa Journal: Prev Med Rep Date: 2022-09-03