| Literature DB >> 32274753 |
Olivier Coux1, Barbara A Zieba2, Silke Meiners3.
Abstract
The proteasome is involved in the regulation of all cellular pathways and consequently plays a central role in the control of cellular homeostasis. Together with its regulators, it is at the frontline, both as an actor and as a target, in human health and when homeostasis is disturbed in disease. In this review, we aim to provide an overview of the many levels at which the functions of the proteasome and its regulators can be regulated to cope with cellular needs or are altered in pathological conditions.Entities:
Keywords: 19S complex; Disease; PA200; PA28; PI31; Proteasome
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Year: 2020 PMID： 32274753 DOI： 10.1007/978-3-030-38266-7_3
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622