OBJECTIVE: Authors review a series of 29 extra-skeletal Ewing Sarcoma (EES). METHODS: They analyzed characteristics, prognostic factors and outcome of EES. RESULTS: Authors report 60% Overall Survival (OS) and 56% of Event Free Survival (EFS) at 5 years. Better 5 years EFS was found in patients with localized disease (68.8%) compared to metastatic EES (33.3%) (p = 0.042). Radiotherapy + surgery offered the best local treatment (p=0.017). Volume (p = 0.032), Surgical margins (p = 0.01), metastatic disease (p = 0.0013) were a significant prognostic factor for OS at 5-yrs. CONCLUSION: Adequate margins and surgery+radiotherapy improve Overall Survival.
OBJECTIVE: Authors review a series of 29 extra-skeletal Ewing Sarcoma (EES). METHODS: They analyzed characteristics, prognostic factors and outcome of EES. RESULTS: Authors report 60% Overall Survival (OS) and 56% of Event Free Survival (EFS) at 5 years. Better 5 years EFS was found in patients with localized disease (68.8%) compared to metastatic EES (33.3%) (p = 0.042). Radiotherapy + surgery offered the best local treatment (p=0.017). Volume (p = 0.032), Surgical margins (p = 0.01), metastatic disease (p = 0.0013) were a significant prognostic factor for OS at 5-yrs. CONCLUSION: Adequate margins and surgery+radiotherapy improve Overall Survival.
Authors: R B Raney; L Asmar; W A Newton; C Bagwell; J C Breneman; W Crist; E A Gehan; B Webber; M Wharam; E S Wiener; J R Anderson; H M Maurer Journal: J Clin Oncol Date: 1997-02 Impact factor: 44.544
Authors: J R Downing; D R Head; D M Parham; E C Douglass; M G Hulshof; M P Link; T A Motroni; H E Grier; A M Curcio-Brint; D N Shapiro Journal: Am J Pathol Date: 1993-11 Impact factor: 4.307
Authors: P Rosito; A F Mancini; R Rondelli; M E Abate; A Pession; L Bedei; G Bacci; P Picci; M Mercuri; P Ruggieri; G Frezza; M Campanacci; G Paolucci Journal: Cancer Date: 1999-08-01 Impact factor: 6.860
Authors: A El Weshi; A Allam; D Ajarim; F Al Dayel; R Pant; S Bazarbashi; M Memon Journal: Clin Oncol (R Coll Radiol) Date: 2010-06 Impact factor: 4.126
Authors: Mark A Applebaum; Jennifer Worch; Katherine K Matthay; Robert Goldsby; John Neuhaus; Daniel C West; Steven G Dubois Journal: Cancer Date: 2011-01-10 Impact factor: 6.860