| Literature DB >> 32273397 |
Hongwei Wang1, Silong Sun2, Wenyang Ge2, Lanfei Zhao2, Bingqian Hou2, Kai Wang3, Zhongfan Lyu2, Liyang Chen3, Shoushen Xu2, Jun Guo4, Min Li2, Peisen Su2, Xuefeng Li2, Guiping Wang2, Cunyao Bo2, Xiaojian Fang2, Wenwen Zhuang2, Xinxin Cheng2, Jianwen Wu2, Luhao Dong2, Wuying Chen2, Wen Li2, Guilian Xiao2, Jinxiao Zhao2, Yongchao Hao2, Ying Xu2, Yu Gao2, Wenjing Liu2, Yanhe Liu2, Huayan Yin2, Jiazhu Li5, Xiang Li2, Yan Zhao2, Xiaoqian Wang2, Fei Ni2, Xin Ma2, Anfei Li2, Steven S Xu6, Guihua Bai7, Eviatar Nevo8, Caixia Gao9, Herbert Ohm10, Lingrang Kong1.
Abstract
Fusarium head blight (FHB), a fungal disease caused by Fusarium species that produce food toxins, currently devastates wheat production worldwide, yet few resistance resources have been discovered in wheat germplasm. Here, we cloned the FHB resistance gene Fhb7 by assembling the genome of Thinopyrum elongatum, a species used in wheat distant hybridization breeding. Fhb7 encodes a glutathione S-transferase (GST) and confers broad resistance to Fusarium species by detoxifying trichothecenes through de-epoxidation. Fhb7 GST homologs are absent in plants, and our evidence supports that Th. elongatum has gained Fhb7 through horizontal gene transfer (HGT) from an endophytic Epichloë species. Fhb7 introgressions in wheat confers resistance to both FHB and crown rot in diverse wheat backgrounds without yield penalty, providing a solution for Fusarium resistance breeding.Entities:
Year: 2020 PMID： 32273397 DOI： 10.1126/science.aba5435
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728