| Literature DB >> 32270621 |
Rajiv Gupta1, Sunil Kumar1, Peter Gow1, Leon Hsien-Cheng Chang2, Linda Yen1.
Abstract
Anti-MDA5-associated dermatomyositis (MDA5-associated DM) is an uncommon presentation of idiopathic inflammatory myositis, typically amyopathic, associated with rapidly progressive, treatment refractory interstitial lung disease and poor prognosis, particularly in patients with concomitant rapidly progressive interstitial lung disease (RP-ILD). We report two cases of MDA5-associated DM with fatal outcome in one of the patients, despite 'aggressive triple therapy' for RP-ILD.Entities:
Keywords: MDA5-associated interstitial lung disease; anti-MDA5-associated dermatomyositis; cyclosporine; inflammatory myopathy; intravenous immunoglobulins
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Year: 2020 PMID： 32270621 DOI： 10.1111/imj.14789
Source DB: PubMed Journal: Intern Med J ISSN： 1444-0903 Impact factor: 2.048