Literature DB >> 32268113

Why Warburg Works: Lactate Controls Immune Evasion through GPR81.

Kathrine Lundø1, Mette Trauelsen2, Stine F Pedersen3, Thue W Schwartz4.   

Abstract

Lactate accumulation in tumors-a hallmark of the Warburg effect-has recently been shown to regulate cancer cell metabolism and survival through autocrine activation of GPR81. Now, Brown et al. (2020) demonstrate that lactate surprisingly also controls immune evasion through paracrine activation of GPR81 on stromal dendritic cells.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2020        PMID： 32268113     DOI： 10.1016/j.cmet.2020.03.001

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  10 in total

Review 1.  Metabolic reprogramming by driver mutation-tumor microenvironment interplay in pancreatic cancer: new therapeutic targets.

Authors:  Henriette Berg Andersen; Renata Ialchina; Stine Falsig Pedersen; Dominika Czaplinska
Journal:  Cancer Metastasis Rev       Date:  2021-12-02       Impact factor: 9.264

2.  Lactate receptor HCAR1 regulates cell growth, metastasis and maintenance of cancer‑specific energy metabolism in breast cancer cells.

Authors:  Lili Jin; Yanan Guo; Jiawen Chen; Zhenzhen Wen; Yibin Jiang; Jing Qian
Journal:  Mol Med Rep       Date:  2022-07-01       Impact factor: 3.423

Review 3.  Lactate shuttle: from substance exchange to regulatory mechanism.

Authors:  Xingchen Wang; He Liu; Yingqian Ni; Peibo Shen; Xiuzhen Han
Journal:  Hum Cell       Date:  2021-10-04       Impact factor: 4.174

4.  A miR-210-3p regulon that controls the Warburg effect by modulating HIF-1α and p53 activity in triple-negative breast cancer.

Authors:  Ye Du; Na Wei; Ruolin Ma; Shuheng Jiang; Dong Song
Journal:  Cell Death Dis       Date:  2020-09-09       Impact factor: 8.469

Review 5.  Metabolism of Dendritic Cells in Tumor Microenvironment: For Immunotherapy.

Authors:  Xin Peng; Youe He; Jun Huang; Yongguang Tao; Shuang Liu
Journal:  Front Immunol       Date:  2021-02-24       Impact factor: 7.561

Review 6.  Metabolic Reprogramming Underlying Brain Metastasis of Breast Cancer.

Authors:  Baoyi Liu; Xin Zhang
Journal:  Front Mol Biosci       Date:  2022-01-05

7.  PI3K-AKT Pathway Modulation by Thymoquinone Limits Tumor Growth and Glycolytic Metabolism in Colorectal Cancer.

Authors:  Shahid Karim; Abdulhadi S Burzangi; Aftab Ahmad; Nasir Ali Siddiqui; Ibrahim M Ibrahim; Priyanka Sharma; Walaa A Abualsunun; Gamal A Gabr
Journal:  Int J Mol Sci       Date:  2022-02-19       Impact factor: 5.923

8.  A Novel Risk Score Model of Lactate Metabolism for Predicting over Survival and Immune Signature in Lung Adenocarcinoma.

Authors:  Zhou Jiang; Yongzhong Luo; Lemeng Zhang; Haitao Li; Changqie Pan; Hua Yang; Tianli Cheng; Jianhua Chen
Journal:  Cancers (Basel)       Date:  2022-07-30       Impact factor: 6.575

9.  Calycosin Inhibits the Malignant Behaviors of Lung Adenocarcinoma Cells by Regulating the circ_0001946/miR-21/GPD1L/HIF-1α Signaling Axis.

Authors:  Lixia Zhou; Wenxian Chen; Hang Yang; Jiaqin Liu; Hui Meng
Journal:  Dis Markers       Date:  2022-08-13       Impact factor: 3.464

10.  Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis.

Authors:  Jingyong Xu; Yao Li; Zhe Li; Weiwei Shao; Jinghai Song; Junmin Wei
Journal:  J Oncol       Date:  2022-01-12       Impact factor: 4.375
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.