| Literature DB >> 32266972 |
Patricia Fernández-Calvo1,2, Sabrina Iñigo1,2, Gaétan Glauser3, Robin Vanden Bossche1,2, Michelle Tang4,5, Baohua Li4, Rebecca De Clercq1,2, Astrid Nagels Durand1,2, Dominique Eeckhout1,2, Kris Gevaert6,7, Geert De Jaeger1,2, Siobhan M Brady8, Daniel J Kliebenstein4,9, Laurens Pauwels1,2, Alain Goossens1,2, Andrés Ritter1,2.
Abstract
The sessile lifestyle of plants requires accurate physiology adjustments to be able to thrive in a changing environment. Plants integrate environmental timing signals to control developmental and stress responses. Here, we identified Far1 Related Sequence (FRS) 7 and FRS12, two transcriptional repressors that accumulate in short-day conditions, as regulators of Arabidopsis glucosinolate (GSL) biosynthesis. Loss of function of FRS7 and FRS12 results in plants with increased amplitudes of diurnal expression of GSL pathway genes. Protein interaction analyses revealed that FRS7 and FRS12 recruit the NOVEL INTERACTOR OF JAZ (NINJA) to assemble a transcriptional repressor complex. Genetic and molecular evidence demonstrated that FRS7, FRS12 and NINJA jointly regulate the expression of GSL biosynthetic genes, and thus constitute a molecular mechanism that modulates specialized metabolite accumulation.Entities:
Keywords: circadian; defense; diurnal; glucosinolate; immune responses; jasmonate; light; rhythms
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Year: 2020 PMID： 32266972 DOI： 10.1111/nph.16586
Source DB: PubMed Journal: New Phytol ISSN： 0028-646X Impact factor: 10.151