Literature DB >> 3226361

Proto-oncogenes II.

P Rosen1.   

Abstract

In reviewing recent literature on activated proto-oncogenes including retroviral infection (without oncogene), translocation and inherited childhood cancer, I have come to the conclusion that activated proto-oncogenes are not involved in development of tumors. There is one exception in which a translocated proto-myc leads to transformation. That is the case of the trangenic mouse embryo where faulty development occurs.

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Year:  1988        PMID: 3226361     DOI: 10.1016/0306-9877(88)90009-6

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  1 in total

1.  Transforming function of proto-ras genes depends on heterologous promoters and is enhanced by specific point mutations.

Authors:  A K Chakraborty; K Cichutek; P H Duesberg
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-15       Impact factor: 11.205

  1 in total

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