Literature DB >> 32262161

A targeted, image-guided and dually locked photoresponsive drug delivery system.

S Karthik1, B N Prashanth Kumar, Moumita Gangopadhyay, Mahitosh Mandal, N D Pradeep Singh.   

Abstract

We have developed a new targeted image-guided photoresponsive drug delivery system (DDS) based on a dual locking strategy. Excitation of the DDS by fluorescent light results in the first unlocking and activation of the drug, and allows real-time monitoring of the prodrug. Extended irradiation results in a second unlocking, giving drug release within cancer cells.

Entities:  

Year:  2014        PMID: 32262161     DOI: 10.1039/c4tb01583e

Source DB:  PubMed          Journal:  J Mater Chem B        ISSN: 2050-750X            Impact factor:   6.331


  1 in total

1.  Cross-Linked Polyphenol-Based Drug Nano-Self-Assemblies Engineered to Blockade Prostate Cancer Senescence.

Authors:  Prashanth K B Nagesh; Pallabita Chowdhury; Elham Hatami; Sonam Kumari; Vivek Kumar Kashyap; Manish K Tripathi; Santosh Wagh; Bernd Meibohm; Subhash C Chauhan; Meena Jaggi; Murali M Yallapu
Journal:  ACS Appl Mater Interfaces       Date:  2019-10-08       Impact factor: 9.229

  1 in total

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