Literature DB >> 3226157

A return to time, cells, systems, and aging: V. Further thoughts on Gompertzian survival dynamics--the geriatric years.

M Witten1.   

Abstract

In this paper, I attempt to address the problem of how to model the survival curve in the later lifespan years; the geriatric years. I present a new general model for a three group population in which the first group represents early life failure (neonatal failure), the second group represents the classical "Gompertzian failure", and the third group represents the later life failure or geriatric failure. Theoretical results are compared to the known biological data. It is demonstrated that this three group model embeds, within itself, a greater variety of the known biological survival dynamics. In particular, this new model resolves some of these issues concerning the failure of the pure Gompertzian to model the later life (geriatric) survival distribution.

Entities:  

Mesh:

Year:  1988        PMID: 3226157     DOI: 10.1016/0047-6374(88)90124-8

Source DB:  PubMed          Journal:  Mech Ageing Dev        ISSN: 0047-6374            Impact factor:   5.432


  4 in total

1.  Deceleration in the age pattern of mortality at older ages.

Authors:  S Horiuchi; J R Wilmoth
Journal:  Demography       Date:  1998-11

2.  Ever since Gompertz.

Authors:  S J Olshansky; B A Carnes
Journal:  Demography       Date:  1997-02

3.  Intrinsic time scaling in survival analysis: application to biological populations.

Authors:  T Eakin
Journal:  Bull Math Biol       Date:  1994-11       Impact factor: 1.758

4.  Onset of mortality increase with age and age trajectories of mortality from all diseases in the four Nordic countries.

Authors:  Josef Dolejs; Petra Marešová
Journal:  Clin Interv Aging       Date:  2017-01-21       Impact factor: 4.458

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.