Literature DB >> 32261416

Biophysical characterisation, antitumor activity and MOF encapsulation of a half-sandwich ruthenium(ii) mitoxantronato system.

S Rojas1, E Quartapelle-Procopio, F J Carmona, M A Romero, J A R Navarro, E Barea.   

Abstract

The novel non-conventional metallodrug [(η6-p-cymene)2Ru2mitoxantronato]Cl2 (1) exhibits redox activity, DNA intercalation ability, cathepsin B and D inhibition and in vitro antitumor activity able to circumvent cisplatin resistance. Moreover, 1 can be successfully incorporated into MIL100(Fe) as a proof of concept of the feasibility of metal-organic frameworks as carriers of non-conventional drugs.

Entities:  

Year:  2013        PMID： 32261416     DOI： 10.1039/c3tb21455a

Source DB:  PubMed          Journal:  J Mater Chem B        ISSN： 2050-750X            Impact factor:   6.331


  2 in total

1.  What are the prospects for using complexes of copper(ii) and zinc(ii) to suppress the vital activity of Mycolicibacterium smegmatis?

Authors:  Irina A Lutsenko; Dmitry E Baravikov; Kseniya A Koshenskova; Mikhail A Kiskin; Yulia V Nelyubina; Petr V Primakov; Yulia K Voronina; Veronika V Garaeva; Dmytry A Aleshin; Teimur M Aliev; Valery N Danilenko; Olga B Bekker; Igor L Eremenko
Journal:  RSC Adv       Date:  2022-02-10       Impact factor: 3.361

2.  Synthesis and characterization of new 1,4-dihydropyran derivatives by novel Ta-MOF nanostructures as reusable nanocatalyst with antimicrobial activity.

Authors:  Irfan Ahmad; Saade Abdalkareem Jasim; Ghulam Yasin; Basim Al-Qargholi; Ali Thaeer Hammid
Journal:  Front Chem       Date:  2022-09-27       Impact factor: 5.545
  2 in total

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