Literature DB >> 32258693

Identification of genetic modifiers of somatic CAG instability in Huntington's Disease by in vivo CRISPR - Cas9 genome editing: PS238.

A Azevedo1,2, M Kovalenko2, M Andrew2, F Zhang3, J Lee2,4, V Wheeler2,4, Mouro R Pinto2,4.   

Abstract

Entities:  

Year:  2017        PMID： 32258693      PMCID： PMC6806764          DOI： 10.1016/j.pbj.2017.07.083

Source DB:  PubMed          Journal:  Porto Biomed J        ISSN： 2444-8664


× No keyword cloud information.
  6 in total

Review 1.  Genetic modifiers of Huntington's disease.

Authors:  James F Gusella; Marcy E MacDonald; Jong-Min Lee
Journal:  Mov Disord       Date:  2014-08-25       Impact factor: 10.338

2.  Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis.

Authors:  Laura Kennedy; Elizabeth Evans; Chiung-Mei Chen; Lyndsey Craven; Peter J Detloff; Margaret Ennis; Peggy F Shelbourne
Journal:  Hum Mol Genet       Date:  2003-10-21       Impact factor: 6.150

Review 3.  Disease-associated repeat instability and mismatch repair.

Authors:  Monika H M Schmidt; Christopher E Pearson
Journal:  DNA Repair (Amst)       Date:  2015-12-12

4.  Identification of Genetic Factors that Modify Clinical Onset of Huntington's Disease.

Authors: 
Journal:  Cell       Date:  2015-07-30       Impact factor: 41.582

5.  Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset.

Authors:  Meera Swami; Audrey E Hendricks; Tammy Gillis; Tiffany Massood; Jayalakshmi Mysore; Richard H Myers; Vanessa C Wheeler
Journal:  Hum Mol Genet       Date:  2009-05-23       Impact factor: 6.150

6.  Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.

Authors:  Ricardo Mouro Pinto; Ella Dragileva; Andrew Kirby; Alejandro Lloret; Edith Lopez; Jason St Claire; Gagan B Panigrahi; Caixia Hou; Kim Holloway; Tammy Gillis; Jolene R Guide; Paula E Cohen; Guo-Min Li; Christopher E Pearson; Mark J Daly; Vanessa C Wheeler
Journal:  PLoS Genet       Date:  2013-10-31       Impact factor: 5.917
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.