| Literature DB >> 32258358 |
Ratna Shila Banstola1, Tetsuya Ogino1, Sachiko Inoue1.
Abstract
Adolescence is not only characterized by a period of exploration and experimentation but also by vulnerability to risk-behaviors (substance-use, suicidal behavior, and sexual behavior) that can have many negative consequences. Given the lack of studies in Nepal and the variable results from international studies on the association of self-esteem, perceived social support (PSS), and social capital (SC) with risk behaviors, this study aimed to assess the role of these factors by specifying different sources of PSS (family, friends, and others) and SC (family, school, and neighbors), and controlling for demographic, socioeconomic-status (SES), family, and school related factors. A total of 943 adolescents (grades 9-11) in 8 schools from 3 provinces in Nepal participated in the study, and were selected by multi-stage, cluster, random sampling. Data were collected through a self-administered questionnaire (response rate; 91.9%). Multivariate logistic regression analysis (<0.05 significance) revealed that family SC (OR = 0.83) and PSS from family (OR = 0.95) were negatively associated with substance-use. Self-esteem (OR = 0.90), family and school SC (OR = 0.80 and 0.91, respectively), and PSS from family and friends (OR = 0.95 and 0.96, respectively) were protective against suicidal risk. None of the independent variables showed a preventive association with sexual behavior, but self-esteem was positively associated (OR = 1.11). Therefore, to improve the likelihood of adolescents becoming healthy adults, family and school level interventions to enhance self-esteem, PSS, and SC are helpful in protecting them against substance use and suicidal behavior. On the other hand, adolescents with high self-esteem are at greater risk for inappropriate sexual behavior and should therefore be monitored.Entities:
Keywords: Adolescence; Perceived social support; Risk-behavior; Self-esteem; Social capital
Year: 2020 PMID: 32258358 PMCID: PMC7115101 DOI: 10.1016/j.ssmph.2020.100570
Source DB: PubMed Journal: SSM Popul Health ISSN: 2352-8273
Descriptive information on adolescents’ sociodemographic characteristics and SES, family, school-related factors, and risk behavior (n = 943).
| Variables | Total | Substance-Use | Suicidal Behavior | Sexual Behavior | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No | Yes | No | Yes | No | Yes | |||||
| 13–15 Years | 388 (41.1) | 311 (80.4) | 76 (19.6) | 0.627 | 344 (88.9) | 43 (11.1) | 0.249 | 342 (88.4) | 45 (11.6) | 0.244 |
| 16–19 Years | 555 (58.9) | 453 (81.6) | 102 (18.4) | 505 (91.2) | 49 (8.8) | 476 (85.8) | 79 (14.2) | |||
| Mean ± Standard Deviation 15.82 ± 1.31 | ||||||||||
| Male | 455 (48.3) | 341 (74.9) | 114 (25.1) | 0.000* | 420 (92.5) | 34 (7.5) | 0.023* | 353 (77.8) | 101 (22.2) | 0.000* |
| Female | 488 (51.7) | 423 (86.9) | 64 (13.1) | 429 (88.1) | 58 (11.9) | 465 (95.3) | 23 (4.7) | |||
| 9 | 317 (33.6) | 253 (79.8) | 64 (20.2) | 0.209 | 276 (87.3) | 40 (12.7) | 0.102 | 272 (85.8) | 45 (14.2) | 0.666 |
| 10 | 314 (33.3) | 248 (79.2) | 65 (20.8) | 289 (92.0) | 25 (8.0) | 276 (88.2) | 37 (11.8) | |||
| 11 | 312 (33.1) | 263 (84.3) | 49 (15.7) | 284 (91.3) | 27 (8.7) | 270 (86.5) | 42 (13.5) | |||
| Brahmin/Chhetri | 333 (35.3) | 267 (80.4) | 65 (19.6) | 0.440 | 297 (89.7) | 34 (0.3) | 0.875 | 281 (84.4) | 52 (15.6) | 0.254 |
| Janajati | 505 (53.6) | 407 (80.6) | 98 (19.4) | 456 (90.3) | 49 (9.7) | 445 (88.3) | 59 (11.7) | |||
| Others (Dalit, Muslim, Terai caste) | 105 (11.1) | 90 (85.7) | 15 (14.3) | 96 (91.4) | 9 (8.6) | 92 (87.6) | 13 (12.4) | |||
| Hindu | 815 (86.4) | 666 (81.8) | 148 (18.2) | 0.158 | 743 (91.3) | 71 (8.7) | 0.006* | 716 (88.0) | 98 (12.0) | 0.010* |
| Others | 128 (13.6) | 98 (76.6) | 30 (23.4) | 106 (83.5) | 21 (16.5) | 102 (79.7) | 26 (20.3) | |||
| Kathmandu | 336 (35.6) | 258 (77.0) | 77 (23.0) | 0.004* | 303 (90.4) | 32 (9.6) | 0.035* | 301 (89.6) | 35 (10.4) | 0.000* |
| Kaski | 361 (38.3) | 290 (80.3) | 71 (19.7) | 316 (87.5) | 45 (12.5) | 286 (79.2) | 75 (20.8) | |||
| Palpa | 246 (26.1) | 216 (87.8) | 30 (12.2) | 230 (93.9) | 15 (6.1) | 231 (94.3) | 14 (5.7) | |||
| Hardly-sufficient | 66 (7.0) | 60 (90.9) | 6 (9.1) | 0.082 | 59 (89.4) | 7 (10.6) | 0.861 | 61 (92.4) | 5 (7.6) | 0.205 |
| Sufficient | 557 (59.1) | 451 (81.1) | 105 (18.9) | 499 (89.9) | 56 (10.1) | 476 (85.5) | 81 (14.5) | |||
| Surplus | 320 (33.9) | 253 (79.1) | 67 (20.9) | 291 (90.9) | 29 (9.1) | 281 (88.1) | 38 (11.9) | |||
| Illiterate | 44 (4.7) | 42 (95.5) | 2 (4.5) | 0.044* | 41 (93.2) | 3 (6.8) | 0.656 | 42 (95.5) | 2 (4.5) | 0.223 |
| Literate | 757 (80.3) | 607 (80.3) | 149 (19.7) | 683 (90.3) | 73 (9.7) | 654 (86.4) | 103 (13.6) | |||
| Don't know | 142 (15.1) | 115 (81.0) | 27 (19.0) | 125 (88.7) | 16 (11.3) | 122 (86.5) | 19 (13.5) | |||
| Illiterate | 105 (11.1) | 85 (81.7) | 19 (18.3) | 0.511 | 97 (92.4) | 8 (7.6) | 0.301 | 93 (88.6) | 12 (11.4) | 0.852 |
| Literate | 700 (74.2) | 572 (81.7) | 128 (18.3) | 633 (90.6) | 66 (9.4) | 606 (86.6) | 94 (13.4) | |||
| Don't know | 138 (14.6) | 107 (77.5) | 31 (22.5) | 119 (86.9) | 18 (13.1) | 119 (86.9) | 18 (13.1) | |||
| Other | 519 (55.0) | 406 (78.4) | 112 (21.6) | 0.018* | 456 (88.0) | 62 (12.0) | 0.012* | 439 (84.6) | 80 (15.4) | 0.024* |
| Home maker | 424 (45.0) | 358 (84.4) | 66 (15.6) | 393 (92.9) | 30 (7.1) | 379 (89.6) | 44 (10.4) | |||
| Not employed | 68 (7.2) | 47 (69.1) | 21 (30.9) | 0.009* | 55 (80.9) | 13 (19.1) | 0.007* | 56 (82.4) | 12 (17.6) | 0.250 |
| Employed | 871 (92.8) | 713 (82.0) | 157 (18.0) | 791 (91.0) | 78 (9.0) | 759 (87.2) | 111 (12.8) | |||
| 529 (56.1) | 440 (83.3) | 88 (16.7) | 476 (90.3) | 51 (9.7) | 454 (86.0) | 74 (14.0) | ||||
| Single | 0.048* | 0.908 | 0.383 | |||||||
| Joint | 414 (43.9) | 324 (78.3) | 90 (21.7) | 373 (90.1) | 41 (9.9) | 364 (87.9) | 50 (12.1) | |||
| Most often | 24 (2.5) | 19 (79.2) | 5 (20.8) | 0.010* | 21 (87.5) | 3 (12.5) | 0.006* | 21 (87.5) | 3 (12.5) | 0.013* |
| Sometimes | 605 (64.2) | 474 (78.3) | 131 (21.7) | 531 (88.1) | 72 (11.9) | 511 (84.5) | 94 (15.5) | |||
| Never | 314 (33.3) | 271 (86.6) | 42 (13.4) | 297 (94.6) | 17 (5.4) | 286 (91.4) | 27 (8.6) | |||
| Most often | 18 (1.9) | 13 (72.2) | 5 (27.8) | 0.084 | 15 (83.3) | 3 (16.7) | 0.000* | 14 (82.4) | 3 (17.6) | 0.528 |
| Sometimes | 77 (8.2) | 56 (72.7) | 21 (27.3) | 59 (76.6) | 18 (23.4) | 64 (83.1) | 13 (16.9) | |||
| Never | 848 (89.9) | 695 (82.1) | 152 (17.9) | 775 (91.6) | 71 (8.4) | 740 (87.3) | 108 (12.7) | |||
| Most often | 789 (83.7) | 646 (82.0) | 142 (18.0) | 0.216 | 716 (91.0) | 71 (9.0) | 0.235 | 684 (86.7) | 105 (13.3) | 0.951 |
| Sometimes | 130 (13.8) | 98 (75.4) | 32 (24.6) | 112 (86.2) | 18 (13.8) | 114 (87.7) | 16 (12.3) | |||
| Never | 24 (2.5) | 20 (83.3) | 4 (16.7) | 21 (87.5) | 3 (12.5) | 20 (87.0) | 3 (13.0) | |||
| Most often | 21 (2.2) | 18 (85.7) | 3 (14.3) | 0.010* | 17 (81.0) | 4 (19.0) | 0.002* | 18 (85.7) | 3 (14.3) | 0.222 |
| Sometimes | 258 (27.4) | 193 (74.8) | 65 (25.2) | 219 (85.2) | 38 (14.8) | 216 (83.7) | 42 (16.3) | |||
| Never | 664 (70.4) | 553 (83.4) | 110 (16.6) | 613 (92.5) | 50 (7.5) | 584 (88.1) | 79 (11.9) | |||
| Most often | 20 (2.1) | 17 (85.0) | 3 (15.0) | 0.155 | 17 (85.0) | 3 (15.0) | 0.099 | 15 (78.9) | 4 (21.1) | 0.191 |
| Sometimes | 174 (18.5) | 132 (75.9) | 42 (24.1) | 148 (86.0) | 24 (14.0) | 145 (83.3) | 29 (16.7) | |||
| Never | 748 (79.4) | 614 (82.2) | 133 (17.8) | 683 (91.3) | 65 (8.7) | 657 (87.8) | 91 (12.2) | |||
| No | 402 (42.6) | 328 (81.8) | 73 (18.2) | 0.641 | 367 (91.5) | 34 (8.5) | 0.248 | 359 (89.5) | 42 (10.5) | 0.036* |
| Yes | 541 (57.4) | 436 (80.6) | 105 (19.4) | 482 (89.3) | 58 (10.7) | 459 (84.8) | 82 (15.2) | |||
| Father No | 443 (47.0) | 376 (84.9) | 67 (15.1) | 0.005* | 407 (91.9) | 36 (8.1) | 0.108 | 388 (87.6) | 55 (12.4) | 0.522 |
| Yes | 500 (53.0) | 388 (77.8) | 111 (22.2) | 442 (88.8) | 56 (11.2) | 430 (86.2) | 69 (13.8) | |||
| Mother No | 811 (86.0) | 671 (82.2) | 139 (17.2) | 0.001* | 736 (90.9) | 74 (9.1) | 0.100 | 715 (88.3) | 95 (11.7) | 0.001* |
| Yes | 132 (14.0) | 93 (70.5) | 39 (29.5) | 113 (86.3) | 18 (13.7) | 103 (78.0) | 29 (22.0) | |||
| Siblings No | 851 (90.2) | 706 (83.1) | 144 (16.9) | 0.000* | 775 (91.3) | 74 (8.7) | 0.001* | 746 (87.8) | 104 (12.2) | 0.010* |
| Yes | 92 (9.8) | 58 (63.0) | 34 (37.0) | 74 (80.4) | 18 (19.6) | 72 (78.3) | 20 (21.) | |||
| Grandparents No | 656 (69.6) | 548 (83.5) | 108 (16.5) | 0.004* | 605 (92.4) | 50 (7.6) | 0.001* | 571 (87.2) | 84 (12.8) | 0.642 |
| Yes | 287 (30.4) | 216 (75.5) | 70 (24.5) | 244 (85.3) | 42 (14.7) | 247 (86.1) | 40 (13.9) | |||
| Inadequate | 25 (2.7) | 17 (68.0) | 8 (32.0) | 0.091 | 22 (88.0) | 3 (12.0) | 0.716 | 15 (62.5) | 9 (37.5) | 0.000* |
| Adequate | 910 (97.3) | 740 (81.4) | 169 (18.6) | 819 (90.2) | 89 (9.8) | 796 (87.5) | 114 (12.5) | |||
| Government/Public | 562 (59.6) | 474 (84.5) | 87 (15.5) | 0.001* | 521 (92.9) | 40 (7.1) | 0.001* | 501 (89.1) | 61 (10.9) | 0.011* |
| Private | 381 (40.4) | 290 (76.1) | 91 (23.9) | 328 (86.3) | 52 (13.7) | 317 (83.4) | 63 (16.6) | |||
| Second, Third division | 278 (29.5) | 226 (81.3) | 52 (18.7) | 0.968 | 252 (91.0) | 25 (9.0) | 0.615 | 248 (89.2) | 30 (10.8) | 0.370 |
| Distinction and First Division | 646 (68.5) | 523 (81.1) | 122 (18.9) | 581 (90.1) | 64 (9.9) | 554 (85.9) | 91 (14.1) | |||
| Others | 19 (2.0) | 15 (78.9) | 4 (21.1) | 16 (84.2) | 3 (15.8) | 16 (84.2) | 3 (15.8) | |||
| No | 282 (29.9) | 235 (83.3) | 47 (16.7) | 0.249 | 252 (89.4) | 30 (10.6) | 0.565 | 255 (90.4) | 27 (9.6) | 0.033* |
| Yes | 660 (70.1) | 528 (80.1) | 131 (19.9) | 596 (90.6) | 62 (9.4) | 562 (85.3) | 97 (14.7) | |||
| No | 644 (68.3) | 570 (88.6) | 73 (11.4) | 0.000* | 598 (93.1) | 44 (6.9) | 0.000* | 597 (92.8) | 46 (7.2) | 0.000* |
| Yes | 299 (31.7) | 194 (64.9) | 105 (35.1) | 251 (83.9) | 48 (16.1) | 221 (73.9) | 78 (26.1) | |||
| No | 837 (88.8) | 699 (83.6) | 137 (16.4) | 0.000* | 764 (91.5) | 71 (8.5) | 0.000* | 768 (91.9) | 68 (8.1) | 0.000* |
| Yes | 106 (11.2) | 65 (61.3) | 41 (38.7) | 85 (80.2) | 21 (19.8) | 50 (47.2) | 56 (52.8) | |||
| No | 869 (92.2) | 727 (83.8) | 141 (16.2) | 0.000* | 794 (91.6) | 73 (8.4) | 0.000* | 778 (89.6) | 90 (10.4) | 0.000* |
| Yes | 74 (7.8) | 37 (50.0) | 37 (50.0) | 55 (74.3) | 19 (25.7) | 40 (54.1) | 34 (45.9) | |||
| No | 142 (15.1) | 93 (65.5) | 49 (34.5) | 0.000* | 114 (80.3) | 28 (19.7) | 0.000* | 108 (76.1) | 34 (23.9) | 0.000* |
| Yes | 801 (84.9) | 671 (83.9) | 129 (16.1) | 735 (92.0) | 64 (8.0) | 710 (88.8) | 90 (11.3) | |||
| No | 149 (15.8) | 110 (73.8) | 39 (26.2) | 0.013* | 118 (79.2) | 31 (20.8) | 0.000* | 124 (83.8) | 24 (16.2) | 0.232 |
| Yes | 794 (84.2) | 654 (82.5) | 139 (17.5) | 731 (92.3) | 61 (7.7) | 694 (87.4) | 100 (12.6) | |||
| No | 131 (13.9) | 90 (68.7) | 41 (31.3) | 0.000* | 106 (80.9) | 25 (19.1) | 0.000* | 99 (75.6) | 32 (24.4) | 0.000* |
| Yes | 811 (86.1) | 673 (83.1) | 137 (16.9) | 742 (91.7) | 67 (8.3) | 718 (88.6) | 92 (11.4) | |||
| No | 205 (21.7) | 154 (75.5) | 50 (24.5) | 0.021* | 172 (83.9) | 33 (16.1) | 0.001* | 156 (76.5) | 48 (23.5) | 0.000* |
| Yes | 738 (78.3) | 610 (82.7) | 128 (17.3) | 677 (92.0) | 59 (8.0) | 662 (89.7) | 76 (10.3) | |||
| No | 907 (96.2) | 743 (82.0) | 163 (18.0) | 0.000* | 821 (90.7) | 84 (9.3) | 0.010* | 791 (87.3) | 115 (12.7) | 0.032* |
| Yes | 36 (3.8) | 21 (58.3) | 15 (41.7) | 28 (77.8) | 8 (22.2) | 27 (75.0) | 9 (25.0) | |||
Numbers in the parentheses indicate percentage, SE; Standard Error *significant P value < 0.05 by chi-square test.
Prevalence of risk behavior with self-esteem, perceived social support, and social capital (n = 943).
| Variables | Total | Substance-Use# | Suicidal Behavior# | Sexual Behavior# | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No | Yes | No | Yes | No | Yes | |||||
| Low | 281 (29.8) | 208 (74.0) | 73 (26.0) | 0.000* | 236 (84.3) | 44 (15.7) | 0.000* | 244 (86.8) | 37 (13.2) | 0.998 |
| High | 662 (70.2) | 556 (84.1) | 105 (15.9) | 613 (92.7) | 48 (7.3) | 574 (86.8) | 87 (13.2) | |||
| Mean ± SE 16.51 ± 0.12 | ||||||||||
| Low and Medium | 185 (19.6) | 120 (65.2) | 64 (34.8) | 0.000* | 146 (79.3) | 38 (20.7) | 0.000* | 147 (79.5) | 38 (20.5) | 0.001* |
| High | 758 (80.4) | 644 (85.0) | 114 (15.0) | 703 (92.9) | 54 (7.1) | 671 (88.6) | 86 (11.4) | |||
| Mean ± SE 23.0 ± 0.17 | ||||||||||
| Low and Medium | 259 (27.5) | 188 (72.9) | 70 (27.1) | 0.000* | 214 (82.9) | 44 (17.1) | 0.000* | 206 (79.5) | 53 (20.5) | 0.000* |
| High | 684 (72.5) | 576 (84.2) | 108 (15.8) | 635 (93.0) | 48 (7.0) | 612 (89.6) | 71 (10.4) | |||
| Mean ± SE 21.39 ± 0.18 | ||||||||||
| Low and Medium | 333 (35.3) | 259 (78.0) | 73 (22.0) | 0.074 | 288 (86.7) | 44 (13.3) | 0.008* | 278 (83.5) | 55 (16.5) | 0.024* |
| High | 610 (64.7) | 505 (82.8) | 105 (17.2) | 561 (92.1) | 48 (7.9) | 540 (88.7) | 69 (11.3) | |||
| Mean ± SE 20.35 ± 0.20 | ||||||||||
| Low | 12 (1.3) | 5 (41.7) | 7 (58.3) | 0.000* | 9 (75.0) | 3 (25.0) | 0.189 | 8 (66.7) | 4 (33.3) | 0.100 |
| High | 929 (98.7) | 757 (81.6) | 171 (18.4) | 839 (90.5) | 88 (9.5) | 808 (87.1) | 120 (12.9) | |||
| Mean ± SE 15.89 ± 0.06 | ||||||||||
| Low | 60 (6.4) | 44 (73.3) | 16 (26.7) | 0.113 | 51 (85.0) | 9 (15.0) | 0.160 | 45 (75.0) | 15 (25.0) | 0.005* |
| High | 882 (93.6) | 719 (81.6) | 162 (18.4) | 797 (90.6) | 83 (9.4) | 772 (87.6) | 109 (12.4) | |||
| Mean ± SE 20.81 ± 0.12 | ||||||||||
| Low | 91 (9.7) | 65 (71.4) | 26 (28.6) | 0.013* | 81 (89.0) | 10 (11.0) | 0.682 | 76 (83.5) | 15 (16.5) | 0.324 |
| High | 852 (90.3) | 699 (82.1) | 152 (17.9) | 768 (90.4) | 82 (9.6) | 742 (87.2) | 109 (12.8) | |||
| Mean ± SE 14.67 ± 0.09 | ||||||||||
Numbers in the parentheses indicate percentage, SE; Standard Error *significant P value < 0.05 by chi-square test # multiple response.
#Substance-use: 178 (18.9%), alcohol 103 (10.9%), smoking tobacco 78 (8.3%), smokeless tobacco 53 (5.6%), marijuana 37 (3.9%), and drug use 9 (1.0%).
#Suicidal behavior: 92 (9.8%), suicidal thought 74 (7.8%), plan 41 (4.3%), attempted 24(2.5%).
#Sexual behavior: 124 (13.2%), watch pornography/sexually explicit material 107 (11.3%), sexual contact 23 (2.4%).
Abbreviations: PSS, perceived social support; SC, social capital.
Odds ratios and confidence intervals for the effect of self-esteem, three sources of social support, and three sources of social capital on substance use, suicidal behavior and sexual behavior of adolescents, controlling all other variables including demographic, SES, family, and school factors (n = 943).
| Substance Use (Yes) | Suicidal Behavior (Yes) | Sexual behavior (Yes) | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Crude Model | Adjusted Model | Crude Model | Adjusted Model | Crude Model | Adjusted Model | |||||||||||||
| OR | LCI | UCI | OR | LCI | UCI | OR | LCI | UCI | OR | LCI | UCI | OR | LCI | UCI | OR | LCI | UCI | |
| Self esteem | 0.93 | 0.89 | 0.97 | 0.95 | 0.90 | 1.00 | 0.85 | 0.80 | 0.91 | 0.90 | 0.83 | 0.96 | 1.02 | 0.97 | 1.08 | 1.11 | 1.04 | 1.19 |
| PSS from family | 0.93 | 0.90 | 0.95 | 0.95 | 0.91 | 0.98 | 0.92 | 0.89 | 0.95 | 0.95 | 0.91 | 0.99 | 0.95 | 0.92 | 0.97 | 0.98 | 0.93 | 1.03 |
| PSS from friends | 0.94 | 0.92 | 0.97 | 0.97 | 0.94 | 1.00 | 0.93 | 0.90 | 0.96 | 0.96 | 0.92 | 0.99 | 0.94 | 0.91 | 0.96 | 0.96 | 0.92 | 1.00 |
| PSS from other significant persons | 0.97 | 0.94 | 0.99 | 1.00 | 0.96 | 1.03 | 0.96 | 0.93 | 0.99 | 0.97 | 0.93 | 1.01 | 0.96 | 0.94 | 0.99 | 0.99 | 0.95 | 1.03 |
| Family social capital | 0.82 | 0.76 | 0.88 | 0.83 | 0.75 | 0.93 | 0.78 | 0.72 | 0.86 | 0.80 | 0.70 | 0.92 | 0.88 | 0.81 | 0.96 | 0.87 | 0.75 | 1.01 |
| School social capital | 0.93 | 0.89 | 0.97 | 1.00 | 0.94 | 1.05 | 0.87 | 0.83 | 0.92 | 0.91 | 0.85 | 0.98 | 0.91 | 0.87 | 0.95 | 0.98 | 0.91 | 1.04 |
| Neighborhood social capital | 0.91 | 0.85 | 0.98 | 0.96 | 0.90 | 1.03 | 0.91 | 0.85 | 0.98 | 0.97 | 0.89 | 1.06 | 0.97 | 0.91 | 1.03 | 1.01 | 0.92 | 1.10 |
OR: odds ratio, CI: confidence interval, LCI: lower confidence interval, UCI: upper confidence interval, SES: socioeconomic status, PSS: perceived social support.
Crude models show ORs and CIs between each independent variable and three types of dependent variables.
Adjusted models show ORs and CIs between each independent variable and three types of dependent variables adjusted for all covariates of demographic, SES, family, and school factors. We removed values for all covariates from this table. See Supplementary Tables 1–7.