Roberta Bonomo1,2,3, Anna Latorre1,4, Bettina Balint1,5, Katarzyna Smilowska6, Lorenzo Rocchi1, John C Rothwell1, Mario Zappia3, Kailash P Bhatia1. 1. Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology, University College London London United Kingdom. 2. Experimental Neurology Unit School of Medicine and Surgery, University of Milano-Bicocca Monza Italy. 3. Department "G.F. Ingrassia", Section of Neurosciences University of Catania Catania Italy. 4. Department of Human Neurosciences Sapienza University of Rome Rome Italy. 5. Department of Neurology University Hospital Heidelberg Heidelberg Germany. 6. Silesian Center of Neurology Katowice Poland.
Abstract
BACKGROUND: Volitional control of involuntary movements has so far been considered a hallmark of tic disorders. However, modulation of involuntary movements can also be observed in other hyperkinesias. CASES: Here, we present 6 patients with chorea able to suppress their involuntary movements, on demand. In 3 of them, surface electromyography was used to quantify degree of suppression and confirmed a reduction of muscle activity up to 68%, during volitional control. CONCLUSION: This observation represents a first step toward a description of a new clinical feature in choreic syndromes and an opportunity to redefine the role of volitional inhibition in hyperkinetic movement disorders.
BACKGROUND: Volitional control of involuntary movements has so far been considered a hallmark of tic disorders. However, modulation of involuntary movements can also be observed in other hyperkinesias. CASES: Here, we present 6 patients with chorea able to suppress their involuntary movements, on demand. In 3 of them, surface electromyography was used to quantify degree of suppression and confirmed a reduction of muscle activity up to 68%, during volitional control. CONCLUSION: This observation represents a first step toward a description of a new clinical feature in choreic syndromes and an opportunity to redefine the role of volitional inhibition in hyperkinetic movement disorders.
Authors: A Berardelli; J Noth; P D Thompson; E L Bollen; A Currà; G Deuschl; J G van Dijk; R Töpper; M Schwarz; R A Roos Journal: Mov Disord Date: 1999-05 Impact factor: 10.338
Authors: Alberto J Espay; Selma Aybek; Alan Carson; Mark J Edwards; Laura H Goldstein; Mark Hallett; Kathrin LaFaver; W Curt LaFrance; Anthony E Lang; Tim Nicholson; Glenn Nielsen; Markus Reuber; Valerie Voon; Jon Stone; Francesca Morgante Journal: JAMA Neurol Date: 2018-09-01 Impact factor: 18.302