Literature DB >> 32257399

NLRP3 inflammasome as a novel therapeutic target for Alzheimer's disease.

Yun Zhang1, Zhifang Dong2, Weihong Song1,2.   

Abstract

Keywords:  Diseases of the nervous system; Neuroimmunology

Year:  2020        PMID： 32257399      PMCID： PMC7109024          DOI： 10.1038/s41392-020-0145-7

Source DB:  PubMed          Journal:  Signal Transduct Target Ther        ISSN： 2059-3635


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  10 in total

Review 1.  The importance of inflammatory mechanisms for the development of Alzheimer's disease.

Authors:  P Eikelenboom; R Veerhuis
Journal:  Exp Gerontol       Date:  1999-06       Impact factor: 4.032

Review 2.  Alzheimer's disease: the amyloid cascade hypothesis.

Authors:  J A Hardy; G A Higgins
Journal:  Science       Date:  1992-04-10       Impact factor: 47.728

Review 3.  Islet amyloid polypeptide: Another key molecule in Alzheimer's pathogenesis?

Authors:  Yun Zhang; Weihong Song
Journal:  Prog Neurobiol       Date:  2017-03-06       Impact factor: 11.685

4.  Glycogen synthase kinase 3 beta induces caspase-cleaved tau aggregation in situ.

Authors:  Jae-Hyeon Cho; Gail V W Johnson
Journal:  J Biol Chem       Date:  2004-10-19       Impact factor: 5.157

5.  Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice.

Authors:  Lauren M Billings; Salvatore Oddo; Kim N Green; James L McGaugh; Frank M LaFerla
Journal:  Neuron       Date:  2005-03-03       Impact factor: 17.173

6.  Alzheimer's disease: paired helical filaments and cytomembranes.

Authors:  E G Gray; M Paula-Barbosa; A Roher
Journal:  Neuropathol Appl Neurobiol       Date:  1987 Mar-Apr       Impact factor: 8.090

7.  Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes.

Authors:  Philip T T Ly; Yili Wu; Haiyan Zou; Ruitao Wang; Weihui Zhou; Ayae Kinoshita; Mingming Zhang; Yi Yang; Fang Cai; James Woodgett; Weihong Song
Journal:  J Clin Invest       Date:  2012-12-03       Impact factor: 14.808

8.  NLRP3 inflammasome activation drives tau pathology.

Authors:  Christina Ising; Carmen Venegas; Shuangshuang Zhang; Hannah Scheiblich; Susanne V Schmidt; Ana Vieira-Saecker; Stephanie Schwartz; Shadi Albasset; Róisín M McManus; Dario Tejera; Angelika Griep; Francesco Santarelli; Frederic Brosseron; Sabine Opitz; James Stunden; Maximilian Merten; Rakez Kayed; Douglas T Golenbock; David Blum; Eicke Latz; Luc Buée; Michael T Heneka
Journal:  Nature       Date:  2019-11-20       Impact factor: 49.962

9.  The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.

Authors:  Annett Halle; Veit Hornung; Gabor C Petzold; Cameron R Stewart; Brian G Monks; Thomas Reinheckel; Katherine A Fitzgerald; Eicke Latz; Kathryn J Moore; Douglas T Golenbock
Journal:  Nat Immunol       Date:  2008-07-11       Impact factor: 25.606

10.  NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.

Authors:  Michael T Heneka; Markus P Kummer; Andrea Stutz; Andrea Delekate; Stephanie Schwartz; Ana Vieira-Saecker; Angelika Griep; Daisy Axt; Anita Remus; Te-Chen Tzeng; Ellen Gelpi; Annett Halle; Martin Korte; Eicke Latz; Douglas T Golenbock
Journal:  Nature       Date:  2012-12-19       Impact factor: 49.962
  10 in total

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