Literature DB >> 32257396

Inhibition of USP14 and UCH37 deubiquitinating activity by b-AP15 as a potential therapy for tumors with p53 deficiency.

Yu-Shui Ma1,2,3,4, Xiao-Feng Wang5, Fei Yu3, Ting-Miao Wu4, Ji-Bin Liu2, Yun-Jie Zhang5, Qing Xia5, Zong-Yuan Jiang6, Qin-Lu Lin7, Da Fu1,4,7.   

Abstract

Keywords:  Drug development; Oncogenes

Year:  2020        PMID： 32257396      PMCID： PMC7109122          DOI： 10.1038/s41392-020-0143-9

Source DB:  PubMed          Journal:  Signal Transduct Target Ther        ISSN： 2059-3635


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  10 in total

1.  Jab1 induces the cytoplasmic localization and degradation of p53 in coordination with Hdm2.

Authors:  Wonkyung Oh; Eun-Woo Lee; Young Hoon Sung; Mi-Ran Yang; Jaewang Ghim; Han-Woong Lee; Jaewhan Song
Journal:  J Biol Chem       Date:  2006-04-19       Impact factor: 5.157

2.  Proteasome subunit Rpn13 is a novel ubiquitin receptor.

Authors:  Koraljka Husnjak; Suzanne Elsasser; Naixia Zhang; Xiang Chen; Leah Randles; Yuan Shi; Kay Hofmann; Kylie J Walters; Daniel Finley; Ivan Dikic
Journal:  Nature       Date:  2008-05-22       Impact factor: 49.962

3.  Inhibition of proteasome deubiquitinating activity as a new cancer therapy.

Authors:  Pádraig D'Arcy; Slavica Brnjic; Maria Hägg Olofsson; Mårten Fryknäs; Kristina Lindsten; Michelandrea De Cesare; Paola Perego; Behnam Sadeghi; Moustapha Hassan; Rolf Larsson; Stig Linder
Journal:  Nat Med       Date:  2011-11-06       Impact factor: 53.440

4.  Tumor spectrum analysis in p53-mutant mice.

Authors:  T Jacks; L Remington; B O Williams; E M Schmitt; S Halachmi; R T Bronson; R A Weinberg
Journal:  Curr Biol       Date:  1994-01-01       Impact factor: 10.834

5.  Enhancement of proteasome activity by a small-molecule inhibitor of USP14.

Authors:  Byung-Hoon Lee; Min Jae Lee; Soyeon Park; Dong-Chan Oh; Suzanne Elsasser; Ping-Chung Chen; Carlos Gartner; Nevena Dimova; John Hanna; Steven P Gygi; Scott M Wilson; Randall W King; Daniel Finley
Journal:  Nature       Date:  2010-09-09       Impact factor: 49.962

6.  Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets.

Authors:  Xiuxiu Lu; Urszula Nowicka; Vinidhra Sridharan; Fen Liu; Leah Randles; David Hymel; Marzena Dyba; Sergey G Tarasov; Nadya I Tarasova; Xue Zhi Zhao; Jun Hamazaki; Shigeo Murata; Terrence R Burke; Kylie J Walters
Journal:  Nat Commun       Date:  2017-06-09       Impact factor: 14.919

7.  Platinum-containing compound platinum pyrithione suppresses ovarian tumor proliferation through proteasome inhibition.

Authors:  Hongbiao Huang; Ni Liu; Yuning Liao; Ningning Liu; Jianyu Cai; Xiaohong Xia; Zhiqiang Guo; Yanling Li; Qirong Wen; Qi Yin; Yan Liu; Qingxia Wu; Dhivya Rajakumar; Xiujie Sheng; Jinbao Liu
Journal:  J Exp Clin Cancer Res       Date:  2017-06-15

8.  MDM4 actively restrains cytoplasmic mTORC1 by sensing nutrient availability.

Authors:  Francesca Mancini; Emanuela Teveroni; Giusy Di Conza; Valentina Monteleone; Ivan Arisi; Marsha Pellegrino; Marianna Buttarelli; Luisa Pieroni; Mara D'Onofrio; Andrea Urbani; Alfredo Pontecorvi; Massimiliano Mazzone; Fabiola Moretti
Journal:  Mol Cancer       Date:  2017-03-07       Impact factor: 27.401

9.  TRIM8 restores p53 tumour suppressor function by blunting N-MYC activity in chemo-resistant tumours.

Authors:  Francesca Mastropasqua; Flaviana Marzano; Alessio Valletti; Italia Aiello; Giuseppe Di Tullio; Annalisa Morgano; Sabino Liuni; Elena Ranieri; Luisa Guerrini; Giuseppe Gasparre; Elisabetta Sbisà; Graziano Pesole; Antonio Moschetta; Mariano Francesco Caratozzolo; Apollonia Tullo
Journal:  Mol Cancer       Date:  2017-03-21       Impact factor: 27.401

Review 10.  Jab1/COPS5 as a Novel Biomarker for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Human Cancer.

Authors:  Guohong Liu; Francois X Claret; Fuling Zhou; Yunbao Pan
Journal:  Front Pharmacol       Date:  2018-02-27       Impact factor: 5.810
  10 in total

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