| Literature DB >> 32253745 |
Yannis Dimitroglou1, Constantina Aggeli2, Konstantinos Rapis2, Dimitrios Maragiannis2,3, Kali Polytarchou2, Konstantinos Gatzoulis2, Eleftherios Tsiamis2, Dimitris Tousoulis2.
Abstract
Vortex formation time (VFT) is a dimensionless index used to quantify duration of vortex ring formation during diastole. We sought to investigate the effect of pharmaceutical stress on VFT in patients evaluated for ischemia. For this purpose, a standard dobutamine stress echo (DSE) protocol was performed in 50 consecutive patients, and VFT was calculated at rest and at peak. VFT was calculated from echocardiography measurements using a previously developed mathematical equation. VFTi was calculated as the percentage of change of VFTpeak, compared with VFTrest. Mean VFTrest was 2.46 (0.73) and mean VFTpeak 1.67 (0.57) with mean VFTi - 30.0% (19.8). In 14 (28%) patients, an ischemic response (DSE+) was documented. VFTi was significantly lower in DSE+ patients a finding which remained significant in the multivariate analysis after adjusting for age, sex, hypertension, diabetes, history of coronary artery disease, and relative increase of heart rate during stress. Graphical Abstract.Entities:
Keywords: Dobutamine stress echocardiography; Ischemia testing; Pharmaceutical stress; Vortex flow analysis; Vortex formation time
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Year: 2020 PMID： 32253745 DOI： 10.1007/s12265-020-09998-z
Source DB: PubMed Journal: J Cardiovasc Transl Res ISSN： 1937-5387 Impact factor: 4.132