Literature DB >> 32253231

Mechanistic Insights for Optimizing PSMA Radioligand Therapy.

Aravind S Ravi Kumar1,2, Michael S Hofman1,2.   

Abstract

PSMA radioligand therapy is a promising new class of therapy for prostate cancer. Heterogeneity of PSMA expression is an important factor explaining variability in clinical results. The ability to visualize the target with theranostics provides unique mechanistic insights. Potential clinically applicable strategies to improve patient selection and optimize therapeutic efficacy are discussed.See related article by Current et al., p. 2946. ©2020 American Association for Cancer Research.

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Year:  2020        PMID: 32253231     DOI: 10.1158/1078-0432.CCR-20-0209

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN: 1078-0432            Impact factor:   12.531


  2 in total

1.  Radionuclide Therapy in Prostate Cancer: from standalone to combination PSMA theranostics.

Authors:  Shahneen Sandhu; Christina Guo; Michael S Hofman
Journal:  J Nucl Med       Date:  2021-08-12       Impact factor: 11.082

2.  First Experiences with 177Lu-PSMA Therapy in Combination with Pembrolizumab or After Pretreatment with Olaparib in Single Patients.

Authors:  Vikas Prasad; Friedemann Zengerling; Jochen P Steinacker; Christian Bolenz; Meinrad Beer; Thomas Wiegel; Matthias Eiber; Neil Fleshner; Ambros J Beer
Journal:  J Nucl Med       Date:  2020-11-27       Impact factor: 10.057

  2 in total

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