Literature DB >> 32250312

Huntington's Disease Clinical Trials Corner: April 2020.

Filipe B Rodrigues1,2,3, Edward J Wild1.   

Abstract

In this edition of the Huntington's Disease Clinical Trials Corner we expand on the UniQure AMT-130 and on the Neurocrine Biosciences KINECT-HD trials, and list all currently registered and ongoing clinical trials in Huntington's disease.

Entities:  

Keywords:  Huntington disease; clinical trials

Mesh：

Substances：

Year:  2020        PMID： 32250312     DOI： 10.3233/JHD-200002

Source DB:  PubMed          Journal:  J Huntingtons Dis        ISSN： 1879-6397


  11 in total

Review 1.  Huntington's Disease: New Frontiers in Therapeutics.

Authors:  Ling Pan; Andrew Feigin
Journal:  Curr Neurol Neurosci Rep       Date:  2021-02-14       Impact factor: 5.081

Review 2.  Current and Possible Future Therapeutic Options for Huntington's Disease.

Authors:  Mackenzie W Ferguson; Connor J Kennedy; Thulani H Palpagama; Henry J Waldvogel; Richard L M Faull; Andrea Kwakowsky
Journal:  J Cent Nerv Syst Dis       Date:  2022-05-21

Review 3.  Adeno-Associated Viral Vectors as Versatile Tools for Neurological Disorders: Focus on Delivery Routes and Therapeutic Perspectives.

Authors:  Ana Fajardo-Serrano; Alberto J Rico; Elvira Roda; Adriana Honrubia; Sandra Arrieta; Goiaz Ariznabarreta; Julia Chocarro; Elena Lorenzo-Ramos; Alvaro Pejenaute; Alfonso Vázquez; José Luis Lanciego
Journal:  Biomedicines       Date:  2022-03-23

Review 4.  A Glimpse of Molecular Biomarkers in Huntington's Disease.

Authors:  Silvia Martí-Martínez; Luis M Valor
Journal:  Int J Mol Sci       Date:  2022-05-12       Impact factor: 6.208

Review 5.  Therapeutic Targeting of MicroRNAs in the Tumor Microenvironment.

Authors:  Rebecca Raue; Ann-Christin Frank; Shahzad Nawaz Syed; Bernhard Brüne
Journal:  Int J Mol Sci       Date:  2021-02-23       Impact factor: 5.923

Review 6.  Innovative Therapeutic Approaches for Huntington's Disease: From Nucleic Acids to GPCR-Targeting Small Molecules.

Authors:  Hidetoshi Komatsu
Journal:  Front Cell Neurosci       Date:  2021-11-26       Impact factor: 5.505

7.  Gene Therapy for Huntington's Disease: The Final Strategy for a Cure?

Authors:  Seulgi Byun; Mijung Lee; Manho Kim
Journal:  J Mov Disord       Date:  2021-11-17

Review 8.  Drugging DNA Damage Repair Pathways for Trinucleotide Repeat Expansion Diseases.

Authors:  Caroline L Benn; Karl R Gibson; David S Reynolds
Journal:  J Huntingtons Dis       Date:  2021

Review 9.  When Good Kinases Go Rogue: GSK3, p38 MAPK and CDKs as Therapeutic Targets for Alzheimer's and Huntington's Disease.

Authors:  Santosh R D'Mello
Journal:  Int J Mol Sci       Date:  2021-05-31       Impact factor: 5.923

10.  The known burden of Huntington disease in the North of Scotland: prevalence of manifest and identified pre-symptomatic gene expansion carriers in the molecular era.

Authors:  Georgios Kounidas; Heather Cruickshank; Stavroula Kastora; Stella Sihlabela; Zosia Miedzybrodzka
Journal:  J Neurol       Date:  2021-04-15       Impact factor: 4.849
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