Literature DB >> 32247740

Possible therapies of Parkinson's disease: A review.

Ashok Chakraborty1, Sam Brauer2, Anil Diwan2.   

Abstract

Parkinson's disease (PD) is a complex condition with a wide range of symptoms, like impaired movement, tremors, apathy and depression, and many other symptoms. The disease results from degeneration of dopaminergic neural cells. No cure at present but symptomatic some palliative treatments are available to slow down the disease progression. According to the Parkinson's Foundation every year in U.S., approximately 60,000 Americans diagnosed with PD. Nearly one million will be living with PD in the U.S. by 2020, which is more than the combined number of people diagnosed with multiple sclerosis, muscular dystrophy and Amyotrophic Lateral Sclerosis (ALS). There is no diagnostic test for PD, yet, but this article will review all kinds symptomatic and disease-modifying therapy.
Copyright © 2020. Published by Elsevier Ltd.

Entities:  

Keywords:  Cell therapy gene therapy; Levodopa therapy; Parkinson’s disease

Year:  2020        PMID: 32247740     DOI: 10.1016/j.jocn.2020.03.024

Source DB:  PubMed          Journal:  J Clin Neurosci        ISSN: 0967-5868            Impact factor:   1.961


  2 in total

1.  Terazosin Analogs Targeting Pgk1 as Neuroprotective Agents: Design, Synthesis, and Evaluation.

Authors:  Yang Wang; Shihu Qian; Fang Zhao; Yujie Wang; Jiaming Li
Journal:  Front Chem       Date:  2022-07-26       Impact factor: 5.545

2.  Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson's disease.

Authors:  Serena Vittorio; Ilenia Adornato; Rosaria Gitto; Samuel Peña-Díaz; Salvador Ventura; Laura De Luca
Journal:  J Enzyme Inhib Med Chem       Date:  2020-12       Impact factor: 5.051

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.