Sebastian Wiberg1, Mathias J Holmberg2, Michael W Donnino3, Jesper Kjaergaard4, Christian Hassager4, Lise Witten2, Katherine M Berg3, Ari Moskowitz3, Lars W Andersen2. 1. Center for Resuscitation Science, Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; Department of Cardiology, The Heart Centre, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark. Electronic address: sebastian.christoph.wiberg@regionh.dk. 2. Center for Resuscitation Science, Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; Research Center for Emergency Medicine, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark. 3. Center for Resuscitation Science, Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA. 4. Department of Cardiology, The Heart Centre, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Abstract
BACKGROUND: While survival after in-hospital cardiac arrest (IHCA) has improved in recent years, it remains unknown whether this trend primarily applies to younger IHCA victims. The aim of this study was to assess trends in survival to hospital discharge after adult IHCA across age groups from 2000 to 2016. METHODS: This is an observational study of IHCA patients included in the Get With The Guidelines®-Resuscitation registry between 2000 and 2016. The primary outcome was survival to hospital discharge. Patients were stratified into five age groups: <50 years, 50-59 years, 60-69 years, 70-79 years, and ≥80 years. Generalized linear regression was used to obtain absolute survival rates over time. RESULTS: A total of 234,767 IHCA patients were included. The absolute increase in survival per calendar year was 0.8% (95% CI 0.7-1.0%, p < 0.001) for patients younger than 50 years, 0.6% (95% CI 0.4-0.7%, p < 0.001) for patients between 50 and 59 years, 0.5% (95% CI 0.4-0.6%, p < 0.001) for patients between 60 and 69 years, 0.5% (95% CI 0.4-0.6%, p < 0.001) for patients between 70 and 79 years, and 0.5% (95% CI 0.4-0.6%, p < 0.001) for patients older than 80 years. We observed a significant interaction between calendar year and age group (p < 0.001), indicating that the rate of improvement in survival over time was significantly different between age groups. CONCLUSIONS: For patients with IHCA, rates of survival to discharge have improved significantly from 2000 to 2016 across all age groups.
BACKGROUND: While survival after in-hospital cardiac arrest (IHCA) has improved in recent years, it remains unknown whether this trend primarily applies to younger IHCA victims. The aim of this study was to assess trends in survival to hospital discharge after adult IHCA across age groups from 2000 to 2016. METHODS: This is an observational study of IHCA patients included in the Get With The Guidelines®-Resuscitation registry between 2000 and 2016. The primary outcome was survival to hospital discharge. Patients were stratified into five age groups: <50 years, 50-59 years, 60-69 years, 70-79 years, and ≥80 years. Generalized linear regression was used to obtain absolute survival rates over time. RESULTS: A total of 234,767 IHCA patients were included. The absolute increase in survival per calendar year was 0.8% (95% CI 0.7-1.0%, p < 0.001) for patients younger than 50 years, 0.6% (95% CI 0.4-0.7%, p < 0.001) for patients between 50 and 59 years, 0.5% (95% CI 0.4-0.6%, p < 0.001) for patients between 60 and 69 years, 0.5% (95% CI 0.4-0.6%, p < 0.001) for patients between 70 and 79 years, and 0.5% (95% CI 0.4-0.6%, p < 0.001) for patients older than 80 years. We observed a significant interaction between calendar year and age group (p < 0.001), indicating that the rate of improvement in survival over time was significantly different between age groups. CONCLUSIONS: For patients with IHCA, rates of survival to discharge have improved significantly from 2000 to 2016 across all age groups.
Authors: Anne C Mosenthal; Robert F Lavery; Michael Addis; Sanjeev Kaul; Steven Ross; Robert Marburger; Edwin A Deitch; David H Livingston Journal: J Trauma Date: 2002-05
Authors: Matilde Winther-Jensen; Tommaso Pellis; Michael Kuiper; Matty Koopmans; Christian Hassager; Niklas Nielsen; Jørn Wetterslev; Tobias Cronberg; David Erlinge; Hans Friberg; Yvan Gasche; Janneke Horn; Jan Hovdenes; Pascal Stammet; Michael Wanscher; Matthew P Wise; Anders Åneman; Jesper Kjaergaard Journal: Resuscitation Date: 2015-01-15 Impact factor: 5.262
Authors: Emelia J Benjamin; Michael J Blaha; Stephanie E Chiuve; Mary Cushman; Sandeep R Das; Rajat Deo; Sarah D de Ferranti; James Floyd; Myriam Fornage; Cathleen Gillespie; Carmen R Isasi; Monik C Jiménez; Lori Chaffin Jordan; Suzanne E Judd; Daniel Lackland; Judith H Lichtman; Lynda Lisabeth; Simin Liu; Chris T Longenecker; Rachel H Mackey; Kunihiro Matsushita; Dariush Mozaffarian; Michael E Mussolino; Khurram Nasir; Robert W Neumar; Latha Palaniappan; Dilip K Pandey; Ravi R Thiagarajan; Mathew J Reeves; Matthew Ritchey; Carlos J Rodriguez; Gregory A Roth; Wayne D Rosamond; Comilla Sasson; Amytis Towfighi; Connie W Tsao; Melanie B Turner; Salim S Virani; Jenifer H Voeks; Joshua Z Willey; John T Wilkins; Jason Hy Wu; Heather M Alger; Sally S Wong; Paul Muntner Journal: Circulation Date: 2017-01-25 Impact factor: 29.690
Authors: Emelia J Benjamin; Paul Muntner; Alvaro Alonso; Marcio S Bittencourt; Clifton W Callaway; April P Carson; Alanna M Chamberlain; Alexander R Chang; Susan Cheng; Sandeep R Das; Francesca N Delling; Luc Djousse; Mitchell S V Elkind; Jane F Ferguson; Myriam Fornage; Lori Chaffin Jordan; Sadiya S Khan; Brett M Kissela; Kristen L Knutson; Tak W Kwan; Daniel T Lackland; Tené T Lewis; Judith H Lichtman; Chris T Longenecker; Matthew Shane Loop; Pamela L Lutsey; Seth S Martin; Kunihiro Matsushita; Andrew E Moran; Michael E Mussolino; Martin O'Flaherty; Ambarish Pandey; Amanda M Perak; Wayne D Rosamond; Gregory A Roth; Uchechukwu K A Sampson; Gary M Satou; Emily B Schroeder; Svati H Shah; Nicole L Spartano; Andrew Stokes; David L Tirschwell; Connie W Tsao; Mintu P Turakhia; Lisa B VanWagner; John T Wilkins; Sally S Wong; Salim S Virani Journal: Circulation Date: 2019-03-05 Impact factor: 29.690
Authors: Rachael T Fothergill; Lynne R Watson; Douglas Chamberlain; Gurkamal K Virdi; Fionna P Moore; Mark Whitbread Journal: Resuscitation Date: 2013-04-11 Impact factor: 5.262
Authors: Saket Girotra; Brahmajee K Nallamothu; John A Spertus; Yan Li; Harlan M Krumholz; Paul S Chan Journal: N Engl J Med Date: 2012-11-15 Impact factor: 91.245
Authors: Oscar J L Mitchell; Eugene Yuriditsky; Nicholas J Johnson; Olivia Doran; David G Buckler; Stacie Neefe; Raghu R Seethala; Sergey Motov; Ari Moskowitz; Jarone Lee; Kelly M Griffin; Michael G S Shashaty; James M Horowitz; Benjamin S Abella Journal: Resuscitation Date: 2021-01-27 Impact factor: 5.262
Authors: Jan Harald Nilsen; Torstein Schanche; Sergei Valkov; Rizwan Mohyuddin; Brage Haaheim; Timofei V Kondratiev; Torvind Næsheim; Gary C Sieck; Torkjel Tveita Journal: Sci Rep Date: 2021-09-23 Impact factor: 4.379