Literature DB >> 32246255

High dose ibuprofen as a monotherapy on an around-the-clock basis fails to control pain in children undergoing tonsil surgery: a prospective observational cohort study.

Philipp Gude1, Franziska Gustedt2, Martin Bellgardt2, Heike Vogelsang2, Jennifer Herzog-Niescery2, Stefan Dazert3, Thomas Peter Weber2, Stefan Volkenstein3.   

Abstract

PURPOSE: The optimal pain management concept in children after tonsil surgery is controversial. Ibuprofen on an "around-the-clock" basis has been suggested to control postoperative pain sufficiently. Therefore, we established a standard scheme with weight-adapted recommended maximum ibuprofen dose. A reliable assessment of pain intensity can be performed with the Children's and Infants' Postoperative Pain Scale (CHIPPS) in children < 5 years, or with the Faces Pain Scale-Revised (FPS-R) in children aged ≥ 5 years. The Parents' Postoperative Pain Measure (PPPM-D) may be a useful tool for both age groups. We hypothesized that not more than 30% of the children would need an opioid rescue medication during their in-hospital stay and analyzed the consistency of the PPPM-D with other pain scales.
METHODS: We included 158 in-patients aged 2-12 years. Ibuprofen was orally administered every 8 h. Three times daily, pain scores were assessed by CHIPPS or FPS-R, respectively. The PPPM-D was used in all children. Exceeding the cut-off value in one of the tools was regarded as relevant pain.
RESULTS: A rescue medication was needed in 82.1% of children after tonsillectomy and 51.3% of children after tonsillotomy (P < 0.001). The cut-off value for relevant pain was mostly exceeded in the PPPM-D, but its overall concordance to the reference scales was low.
CONCLUSION: High-dose ibuprofen "around-the-clock" is insufficient to control pain in children after tonsil surgery. Research is needed to find an optimal schema for management and assessment of postoperative pain.

Entities:  

Keywords:  Analgesics; Child, hospitalized; Fluid therapy; Pain; Pain measurement; Postoperative; Tonsillectomy

Mesh:

Substances:

Year:  2020        PMID: 32246255     DOI: 10.1007/s00405-020-05929-5

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  2 in total

Review 1.  Ibuprofen in the treatment of children's inflammatory pain: a clinical and pharmacological overview.

Authors:  Massimo Barbagallo; Paola Sacerdote
Journal:  Minerva Pediatr       Date:  2019-02       Impact factor: 1.312

Review 2.  As required versus fixed schedule analgesic administration for postoperative pain in children.

Authors:  Anna Hobson; Philip J Wiffen; Joy A Conlon
Journal:  Cochrane Database Syst Rev       Date:  2015-02-26
  2 in total

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