Literature DB >> 32243798

A New Rapid-Acting Antidepressant.

John H Krystal1, Dennis S Charney2, Ronald S Duman2.   

Abstract

The discovery of the strikingly rapid and robust antidepressant effects of r/s-ketamine for the treatment of antidepressant-resistant symptoms of depression has led to new insights into the biology of antidepressants and the FDA approval of its s-isomer, Esketamine (Spravato), the first mechanistically new treatment for depression in over 60 years. To view this Bench to Bedside, open or download the PDF.
Copyright © 2020. Published by Elsevier Inc.

Entities:  

Year:  2020        PMID： 32243798     DOI： 10.1016/j.cell.2020.02.033

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  6 in total

1.  The Rapid and Long-Lasting Antidepressant Effects of Iridoid Fraction in Gardenia Jasminoides J.Ellis Are Dependent on Activating PKA-CREB Signaling Pathway.

Authors:  Li Ren; Hailou Zhang; Weiwei Tao; Yin Chen; Zhilu Zou; XiaoYan Guo; Qinqin Shen; Quansheng Feng; Jingqing Hu
Journal:  Front Pharmacol       Date:  2022-06-08       Impact factor: 5.988

Review 2.  Orphan G Protein Coupled Receptors in Affective Disorders.

Authors:  Lyndsay R Watkins; Cesare Orlandi
Journal:  Genes (Basel)       Date:  2020-06-24       Impact factor: 4.096

3.  S-ketamine as an adjuvant in patient-controlled intravenous analgesia for preventing postpartum depression: a randomized controlled trial.

Authors:  Yaqian Han; Pule Li; Mengrong Miao; Yuan Tao; Xia Kang; Jiaqiang Zhang
Journal:  BMC Anesthesiol       Date:  2022-02-16       Impact factor: 2.217

Review 4.  Depression in Adolescence and Brain-Derived Neurotrophic Factor.

Authors:  Boyoung Lee; Eunjin Shin; Inwoong Song; Bomi Chang
Journal:  Front Mol Neurosci       Date:  2022-07-07       Impact factor: 6.261

5.  Effects of subanaesthetic S-ketamine on postoperative delirium and cognitive function in elderly patients undergoing non-cardiac thoracic surgery: a protocol for a randomised, double-blinded, placebo-controlled and positive-controlled, non-inferiority trial (SKED trial).

Authors:  Wei Wei; Anyu Zhang; Lv Liu; Xi Zheng; Chunlin Tang; Ming Zhou; Yu Gu; Yonghua Yao
Journal:  BMJ Open       Date:  2022-08-01       Impact factor: 3.006

6.  miR-218 in Adolescence Predicts and Mediates Vulnerability to Stress.

Authors:  Angélica Torres-Berrío; Alice Morgunova; Michel Giroux; Santiago Cuesta; Eric J Nestler; Cecilia Flores
Journal:  Biol Psychiatry       Date:  2020-11-02       Impact factor: 13.382
  6 in total

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