Literature DB >> 32243791

Snapshot: Trial Types in Precision Medicine.

Dane Dickson1, Jennifer Johnson2, Raymond Bergan3, Rebecca Owens4, Vivek Subbiah5, Razelle Kurzrock6.   

Abstract

Integrating precision diagnostics into personalized treatments requires understanding how biomarkers relate to clinical outcomes. Various clinical data collection methods exist, each with strengths and weaknesses. Interventional data are high quality but narrowly focused. Real-world data (RWD) provide broader information but with variable quality. Master protocols allow better efficiency in data collection. The master observational trial bridges the gap between interventional and retrospective RWD collection methods. To view this SnapShot, open or download the PDF.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Year:  2020        PMID: 32243791     DOI: 10.1016/j.cell.2020.02.032

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  3 in total

Review 1.  Overcoming cancer therapeutic bottleneck by drug repurposing.

Authors:  Zhe Zhang; Li Zhou; Na Xie; Edouard C Nice; Tao Zhang; Yongping Cui; Canhua Huang
Journal:  Signal Transduct Target Ther       Date:  2020-07-02

2.  Cancer at the time of the COVID-19 hurricane.

Authors:  Giovanni Blandino
Journal:  J Exp Clin Cancer Res       Date:  2020-04-29

Review 3.  Clinical trial design in the era of precision medicine.

Authors:  Elena Fountzilas; Apostolia M Tsimberidou; Henry Hiep Vo; Razelle Kurzrock
Journal:  Genome Med       Date:  2022-08-31       Impact factor: 15.266

  3 in total

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